An antagonist of lipid A action in mammals has complex effects on lipid A induction of defence responses in the model plant Arabidopsis thaliana
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Lipopolysaccharides, the ubiquitous part of the outer membrane of Gram-negative bacteria, and their derivatives are recognised by plants to trigger or potentiate particular defence responses such as induction of genes encoding pathogenesis-related proteins. The molecular mechanisms of LPS perception that underpin these effects in plants are, however, unknown. Here, lipid A from Halomonas magadiensis, which is an antagonist of lipid A action in human cells, was used to investigate lipid A action in plants. Our findings offer an insight into the different structural requirements for direct induction and potentiation of plant defences by lipid A.
Originalsprog | Engelsk |
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Tidsskrift | Microbes and Infection |
Vol/bind | 10 |
Udgave nummer | 5 |
Sider (fra-til) | 571-574 |
Antal sider | 4 |
ISSN | 1286-4579 |
DOI | |
Status | Udgivet - 2008 |
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ID: 8106925