Is reduction in appetite beneficial for body weight management in the context of overweight and obesity? Yes, according to the SATIN (Satiety Innovation) study
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Is reduction in appetite beneficial for body weight management in the context of overweight and obesity? Yes, according to the SATIN (Satiety Innovation) study. / Hansen, Thea Toft; Mead, Bethan R; García-Gavilán, Jesús Francisco; Korndal, Sanne Kellebjerg; Harrold, Joanne A.; Camacho-Barcía, Lucia; Ritz, Christian; Christiansen, Paul; Salas-Salvadó, Jordi; Hjorth, Mads Fiil; Blundell, John; Bulló, Mònica; Halford, Jason C G; Sjödin, Anders Mikael.
I: Journal of Nutritional Science, Bind 8, e39, 2019.Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt
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TY - JOUR
T1 - Is reduction in appetite beneficial for body weight management in the context of overweight and obesity? Yes, according to the SATIN (Satiety Innovation) study
AU - Hansen, Thea Toft
AU - Mead, Bethan R
AU - García-Gavilán, Jesús Francisco
AU - Korndal, Sanne Kellebjerg
AU - Harrold, Joanne A.
AU - Camacho-Barcía, Lucia
AU - Ritz, Christian
AU - Christiansen, Paul
AU - Salas-Salvadó, Jordi
AU - Hjorth, Mads Fiil
AU - Blundell, John
AU - Bulló, Mònica
AU - Halford, Jason C G
AU - Sjödin, Anders Mikael
N1 - CURIS 2019 NEXS 405
PY - 2019
Y1 - 2019
N2 - New dietary-based concepts are needed for treatment and effective prevention of overweight and obesity. The primary objective was to investigate if reduction in appetite is associated with improved weight loss maintenance. This cohort study was nested within the European Commission project Satiety Innovation (SATIN). Participants achieving ≥8% weight loss during an initial 8-week low-energy formula diet were included in a 12-week randomised double-blind parallel weight loss maintenance intervention. The intervention included food products designed to reduce appetite or matching controls along with instructions to follow national dietary guidelines. Appetite was assessed by ad libitum energy intake and self-reported appetite evaluations using visual analogue scales during standardised appetite probe days. These were evaluated at the first day of the maintenance period compared with baseline (acute effects after a single exposure of intervention products) and post-maintenance compared with baseline (sustained effects after repeated exposures of intervention products) regardless of randomisation. A total of 181 participants (forty-seven men and 134 women) completed the study. Sustained reduction in 24-h energy intake was associated with improved weight loss maintenance (R 0·37; P = 0·001), whereas the association was not found acutely (P = 0·91). Suppression in self-reported appetite was associated with improved weight loss maintenance both acutely (R −0·32; P = 0·033) and sustained (R −0·33; P = 0·042). Reduction in appetite seems to be associated with improved body weight management, making appetite-reducing food products an interesting strategy for dietary-based concepts.
AB - New dietary-based concepts are needed for treatment and effective prevention of overweight and obesity. The primary objective was to investigate if reduction in appetite is associated with improved weight loss maintenance. This cohort study was nested within the European Commission project Satiety Innovation (SATIN). Participants achieving ≥8% weight loss during an initial 8-week low-energy formula diet were included in a 12-week randomised double-blind parallel weight loss maintenance intervention. The intervention included food products designed to reduce appetite or matching controls along with instructions to follow national dietary guidelines. Appetite was assessed by ad libitum energy intake and self-reported appetite evaluations using visual analogue scales during standardised appetite probe days. These were evaluated at the first day of the maintenance period compared with baseline (acute effects after a single exposure of intervention products) and post-maintenance compared with baseline (sustained effects after repeated exposures of intervention products) regardless of randomisation. A total of 181 participants (forty-seven men and 134 women) completed the study. Sustained reduction in 24-h energy intake was associated with improved weight loss maintenance (R 0·37; P = 0·001), whereas the association was not found acutely (P = 0·91). Suppression in self-reported appetite was associated with improved weight loss maintenance both acutely (R −0·32; P = 0·033) and sustained (R −0·33; P = 0·042). Reduction in appetite seems to be associated with improved body weight management, making appetite-reducing food products an interesting strategy for dietary-based concepts.
KW - Faculty of Science
KW - Satiety
KW - Hunger
KW - Food innovation
KW - Weight loss
KW - Weight maintenance
U2 - 10.1017/jns.2019.36
DO - 10.1017/jns.2019.36
M3 - Journal article
C2 - 32042406
VL - 8
JO - Journal of Nutritional Science
JF - Journal of Nutritional Science
SN - 2048-6790
M1 - e39
ER -
ID: 236169997