Towards on-site pathogen detection using antibody-based sensors
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Towards on-site pathogen detection using antibody-based sensors. / Skottrup, Peter Durand; Nicolaisen, Mogens; Justesen, Annemarie Fejer.
I: Biosensors and Bioelectronics, Bind 24, Nr. 3, 2008, s. 339-348.Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt
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TY - JOUR
T1 - Towards on-site pathogen detection using antibody-based sensors
AU - Skottrup, Peter Durand
AU - Nicolaisen, Mogens
AU - Justesen, Annemarie Fejer
PY - 2008
Y1 - 2008
N2 - In this paper the recent progress within biosensors for plant pathogen detection will be reviewed. Bio-recognition layers on sensors can be designed in various ways, however the most popular approach is to immobilise antibodies for specific capture of analytes. Focus will be put on antibody surface-immobilisation strategies as well as the use of antibodies in the widely used sensors, quartz crystal microbalance, surface plasmon resonance and cantilevers. We will describe the available data on antibody-based plant pathogen detection and furthermore use examples from detection of the pathogens Salmonella, Listeria monocytogenes, Streptococcus mutans, Bacillus cereus, Bacillus anthracis, Campylobacter and Escherichia coli. We will touch upon optimal assay design and further discuss the strengths and limitations of current sensor technologies for detection of viruses, bacteria and fungi.
AB - In this paper the recent progress within biosensors for plant pathogen detection will be reviewed. Bio-recognition layers on sensors can be designed in various ways, however the most popular approach is to immobilise antibodies for specific capture of analytes. Focus will be put on antibody surface-immobilisation strategies as well as the use of antibodies in the widely used sensors, quartz crystal microbalance, surface plasmon resonance and cantilevers. We will describe the available data on antibody-based plant pathogen detection and furthermore use examples from detection of the pathogens Salmonella, Listeria monocytogenes, Streptococcus mutans, Bacillus cereus, Bacillus anthracis, Campylobacter and Escherichia coli. We will touch upon optimal assay design and further discuss the strengths and limitations of current sensor technologies for detection of viruses, bacteria and fungi.
KW - Former Faculty of Pharmaceutical Sciences
U2 - doi:10.1016/j.bios.2008.06.045
DO - doi:10.1016/j.bios.2008.06.045
M3 - Journal article
VL - 24
SP - 339
EP - 348
JO - Biosensors and Bioelectronics
JF - Biosensors and Bioelectronics
SN - 0956-5663
IS - 3
ER -
ID: 33226340