Advanced microscopy of microbial cells
Research output: Contribution to journal › Journal article › Research › peer-review
Growing awareness of heterogeneity in cells of microbial populations has emphasized the importance of advanced microscopy for visualization and understanding of the molecular mechanisms underlying cell-to-cell variation. In this review, we highlight some of the recent advances in confocal microscopy, super-resolution optical microscopy (STED, SIM, PALM) as well as atomic force microscopy and Raman spectroscopy. Using examples of bistability in microbial populations as well as biofilm development and differentiation in bacterial and yeast consortia, we demonstrate the importance of microscopy for visualization of variation between cells in phenotypic traits such as gene expression.
Original language | English |
---|---|
Book series | Advances in Biochemical Engineering. Biotechnology |
Volume | 124 |
Pages (from-to) | 21-54 |
Number of pages | 34 |
ISSN | 0724-6145 |
DOIs | |
Publication status | Published - 2011 |
- Faculty of Science - Advanced microscopy techniques, Single-cell gene expression, Bistability, Biofilm development and differentiation, Bacteria, Yeast
Research areas
ID: 35231856