vcfpp: a C++ API for rapid processing of the variant call format
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Motivation: Given the widespread use of the variant call format (VCF/BCF) coupled with continuous surge in big data, there remains a perpetual demand for fast and flexible methods to manipulate these comprehensive formats across various programming languages. Results: This work presents vcfpp, a Cþþ API of HTSlib in a single file, providing an intuitive interface to manipulate VCF/BCF files rapidly and safely, in addition to being portable. Moreover, this work introduces the vcfppR package to demonstrate the development of a high-performance R package with vcfpp, allowing for rapid and straightforward variants analyses. Availability and implementation: vcfpp is available from https://github.com/Zilong-Li/vcfpp under MIT license. vcfppR is available from https://cran.r-project.org/web/packages/vcfppR.
Original language | English |
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Article number | btae049 |
Journal | Bioinformatics |
Volume | 40 |
Issue number | 2 |
Number of pages | 4 |
ISSN | 1367-4803 |
DOIs | |
Publication status | Published - 2024 |
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