Vasoactive intestinal polypeptide (VIP) in the pig pancreas: role of VIPergic nerves in control of fluid and bicarbonate secretion

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Vasoactive intestinal polypeptide (VIP) in the pig pancreas : role of VIPergic nerves in control of fluid and bicarbonate secretion. / Poulsen, Steen Seier.

In: Regulatory Peptides, Vol. 8, No. 3, 04.1984, p. 245-59.

Research output: Contribution to journal › Journal article › Research › peer-review

Harvard

Poulsen, SS 1984, 'Vasoactive intestinal polypeptide (VIP) in the pig pancreas: role of VIPergic nerves in control of fluid and bicarbonate secretion', Regulatory Peptides, vol. 8, no. 3, pp. 245-59.

APA

Poulsen, S. S. (1984). Vasoactive intestinal polypeptide (VIP) in the pig pancreas: role of VIPergic nerves in control of fluid and bicarbonate secretion. Regulatory Peptides, 8(3), 245-59.

Vancouver

Poulsen SS. Vasoactive intestinal polypeptide (VIP) in the pig pancreas: role of VIPergic nerves in control of fluid and bicarbonate secretion. Regulatory Peptides. 1984 Apr;8(3):245-59.

Author

Poulsen, Steen Seier. / Vasoactive intestinal polypeptide (VIP) in the pig pancreas : role of VIPergic nerves in control of fluid and bicarbonate secretion. In: Regulatory Peptides. 1984 ; Vol. 8, No. 3. pp. 245-59.

Bibtex

@article{035d289a479e400ebc91d847eccf6626,
title = "Vasoactive intestinal polypeptide (VIP) in the pig pancreas: role of VIPergic nerves in control of fluid and bicarbonate secretion",
abstract = "Vasoactive intestinal polypeptide (VIP) in the pig pancreas is localized to nerves, many of which travel along the pancreatic ducts. VIP stimulates pancreatic fluid and bicarbonate secretion like secretin. Electrical vagal stimulation in the pig causes an atropine-resistant profuse secretion of bicarbonate-rich pancreatic juice. In an isolated perfused preparation of the pig pancreas with intact vagal nerve supply, electrical vagal stimulation caused an atropine-resistant release of VIP, which accurately parallelled the exocrine secretion of juice and bicarbonate. Perfusion of the pancreas with a potent VIP-antiserum inhibited the effect of vagal stimulation on the exocrine secretion. It is concluded, that VIP is responsible for (at least part of) the neurally controlled fluid and bicarbonate secretion from the pig pancreas.",
keywords = "Animals, Bicarbonates, Electric Stimulation, Immunoenzyme Techniques, Pancreas, Pancreatic Juice, Perfusion, Swine, Vagus Nerve, Vasoactive Intestinal Peptide",
author = "Poulsen, {Steen Seier}",
year = "1984",
month = apr,
language = "English",
volume = "8",
pages = "245--59",
journal = "Regulatory Peptides",
issn = "0167-0115",
publisher = "Elsevier",
number = "3",

}

RIS

TY - JOUR

T1 - Vasoactive intestinal polypeptide (VIP) in the pig pancreas

T2 - role of VIPergic nerves in control of fluid and bicarbonate secretion

AU - Poulsen, Steen Seier

PY - 1984/4

Y1 - 1984/4

N2 - Vasoactive intestinal polypeptide (VIP) in the pig pancreas is localized to nerves, many of which travel along the pancreatic ducts. VIP stimulates pancreatic fluid and bicarbonate secretion like secretin. Electrical vagal stimulation in the pig causes an atropine-resistant profuse secretion of bicarbonate-rich pancreatic juice. In an isolated perfused preparation of the pig pancreas with intact vagal nerve supply, electrical vagal stimulation caused an atropine-resistant release of VIP, which accurately parallelled the exocrine secretion of juice and bicarbonate. Perfusion of the pancreas with a potent VIP-antiserum inhibited the effect of vagal stimulation on the exocrine secretion. It is concluded, that VIP is responsible for (at least part of) the neurally controlled fluid and bicarbonate secretion from the pig pancreas.

AB - Vasoactive intestinal polypeptide (VIP) in the pig pancreas is localized to nerves, many of which travel along the pancreatic ducts. VIP stimulates pancreatic fluid and bicarbonate secretion like secretin. Electrical vagal stimulation in the pig causes an atropine-resistant profuse secretion of bicarbonate-rich pancreatic juice. In an isolated perfused preparation of the pig pancreas with intact vagal nerve supply, electrical vagal stimulation caused an atropine-resistant release of VIP, which accurately parallelled the exocrine secretion of juice and bicarbonate. Perfusion of the pancreas with a potent VIP-antiserum inhibited the effect of vagal stimulation on the exocrine secretion. It is concluded, that VIP is responsible for (at least part of) the neurally controlled fluid and bicarbonate secretion from the pig pancreas.

KW - Animals

KW - Bicarbonates

KW - Electric Stimulation

KW - Immunoenzyme Techniques

KW - Pancreas

KW - Pancreatic Juice

KW - Perfusion

KW - Swine

KW - Vagus Nerve

KW - Vasoactive Intestinal Peptide

M3 - Journal article

C2 - 6379759

VL - 8

SP - 245

EP - 259

JO - Regulatory Peptides

JF - Regulatory Peptides

SN - 0167-0115

IS - 3

ER -

ID: 47489352