The first example of a new type of acyclic, achiral nucleoside analogue: 1-[3-hydroxy-2-(hydroxymethyl)prop-1-enyl]thymine

Research output: Contribution to journalJournal articleResearchpeer-review

  • Daniel Sejer Pedersen
  • T. Boesen
  • A.B. Eldrup
  • B. Kiær
  • C. Madsen
  • U. Henriksen
  • O. Dahl
Various preparative routes to 1-(dihydroxyalk-1-enyl)thymines, which are acyclic, achiral nucleoside analogues, have been examined, and a successful synthesis of 1-[3-hydroxy-2-(hydroxymethyl)prop-1-enyl]thymine (1, B = T) has been devised.
Original languageEnglish
JournalOrganic & Biomolecular Chemistry
Issue number14
Pages (from-to)1656-1661
Number of pages6
ISSN1472-7781
Publication statusPublished - 1 Jan 2001
Externally publishedYes

ID: 49635120