The effect of compression stocking on leg edema and discomfort during a 3-hour flight: A randomized controlled trial
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The effect of compression stocking on leg edema and discomfort during a 3-hour flight : A randomized controlled trial. / Olsen, Joachim H H; Öberg, Stina; Rosenberg, Jacob.
In: European Journal of Internal Medicine, Vol. 62, 04.2019, p. 54-57.Research output: Contribution to journal › Journal article › Research › peer-review
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TY - JOUR
T1 - The effect of compression stocking on leg edema and discomfort during a 3-hour flight
T2 - A randomized controlled trial
AU - Olsen, Joachim H H
AU - Öberg, Stina
AU - Rosenberg, Jacob
N1 - Copyright © 2019 European Federation of Internal Medicine. Published by Elsevier B.V. All rights reserved.
PY - 2019/4
Y1 - 2019/4
N2 - BACKGROUND: Compression stockings reduce the risk of thromboembolic complications, leg edema, and edema-related pain and discomfort during long-haul flights. The aim of this study was to assess if compression stockings reduce leg edema, pain, and discomfort during a three-hour flight.METHODS: This randomized controlled trial had a paired design as participants were randomized to wear a compression stocking on one leg during a three-hour flight with the other leg acting as control. Eligibility criteria were adults aged 18-60 years living in Denmark without medical indication for wearing compression stockings during flights. The primary outcome was the change in difference of ankle circumference between legs with and without compression stocking pre- and post-flight. Secondary outcomes were changes in difference of calf circumference, pain, and discomfort pre- and post-flight. All outcomes were self-reported with measurements and questionnaires.RESULTS: A total of 34 participants, median age 31 years (range 25-54), were randomized with complete follow-up. Difference in ankle circumference was median 5 mm larger post-flight compared with pre-flight (interquartile range (IQR) = 0-9, p = .001) and the corresponding change in calf circumference difference was median 5 mm (IQR = 1-12, p < .001). Ankle- and calf circumferences decreased in the leg wearing compression stocking and increased in the other leg. There was no change in difference of pain and discomfort and no adverse events.CONCLUSION: Compression stockings reduced edema formation in young healthy passengers during a three-hour flight. Passengers experiencing edema-related discomfort during short-haul flights may benefit from wearing compression stockings during air travel.TRIAL REGISTRATION: clinicaltrials.gov: NCT03546725.
AB - BACKGROUND: Compression stockings reduce the risk of thromboembolic complications, leg edema, and edema-related pain and discomfort during long-haul flights. The aim of this study was to assess if compression stockings reduce leg edema, pain, and discomfort during a three-hour flight.METHODS: This randomized controlled trial had a paired design as participants were randomized to wear a compression stocking on one leg during a three-hour flight with the other leg acting as control. Eligibility criteria were adults aged 18-60 years living in Denmark without medical indication for wearing compression stockings during flights. The primary outcome was the change in difference of ankle circumference between legs with and without compression stocking pre- and post-flight. Secondary outcomes were changes in difference of calf circumference, pain, and discomfort pre- and post-flight. All outcomes were self-reported with measurements and questionnaires.RESULTS: A total of 34 participants, median age 31 years (range 25-54), were randomized with complete follow-up. Difference in ankle circumference was median 5 mm larger post-flight compared with pre-flight (interquartile range (IQR) = 0-9, p = .001) and the corresponding change in calf circumference difference was median 5 mm (IQR = 1-12, p < .001). Ankle- and calf circumferences decreased in the leg wearing compression stocking and increased in the other leg. There was no change in difference of pain and discomfort and no adverse events.CONCLUSION: Compression stockings reduced edema formation in young healthy passengers during a three-hour flight. Passengers experiencing edema-related discomfort during short-haul flights may benefit from wearing compression stockings during air travel.TRIAL REGISTRATION: clinicaltrials.gov: NCT03546725.
KW - Adult
KW - Air Travel
KW - Ankle/blood supply
KW - Denmark
KW - Edema/prevention & control
KW - Female
KW - Humans
KW - Leg/blood supply
KW - Male
KW - Middle Aged
KW - Self Report
KW - Stockings, Compression
KW - Venous Thrombosis/prevention & control
U2 - 10.1016/j.ejim.2019.01.013
DO - 10.1016/j.ejim.2019.01.013
M3 - Journal article
C2 - 30738701
VL - 62
SP - 54
EP - 57
JO - European Journal of Internal Medicine
JF - European Journal of Internal Medicine
SN - 0953-6205
ER -
ID: 234274326