Immunohistochemical demonstration of a hitherto undescribed localization of hemoglobin A and F in endodermal cells of normal human yolk sac and endodermal sinus tumor.

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Immunohistochemical demonstration of a hitherto undescribed localization of hemoglobin A and F in endodermal cells of normal human yolk sac and endodermal sinus tumor. / Albrechtsen, R; Wewer, U; Wimberley, P D.

In: Acta pathologica et microbiologica Scandinavica. Section A, Pathology, Vol. 88, No. 3, 1980, p. 175-8.

Research output: Contribution to journalJournal articleResearchpeer-review

Harvard

Albrechtsen, R, Wewer, U & Wimberley, PD 1980, 'Immunohistochemical demonstration of a hitherto undescribed localization of hemoglobin A and F in endodermal cells of normal human yolk sac and endodermal sinus tumor.', Acta pathologica et microbiologica Scandinavica. Section A, Pathology, vol. 88, no. 3, pp. 175-8.

APA

Albrechtsen, R., Wewer, U., & Wimberley, P. D. (1980). Immunohistochemical demonstration of a hitherto undescribed localization of hemoglobin A and F in endodermal cells of normal human yolk sac and endodermal sinus tumor. Acta pathologica et microbiologica Scandinavica. Section A, Pathology, 88(3), 175-8.

Vancouver

Albrechtsen R, Wewer U, Wimberley PD. Immunohistochemical demonstration of a hitherto undescribed localization of hemoglobin A and F in endodermal cells of normal human yolk sac and endodermal sinus tumor. Acta pathologica et microbiologica Scandinavica. Section A, Pathology. 1980;88(3):175-8.

Author

Albrechtsen, R ; Wewer, U ; Wimberley, P D. / Immunohistochemical demonstration of a hitherto undescribed localization of hemoglobin A and F in endodermal cells of normal human yolk sac and endodermal sinus tumor. In: Acta pathologica et microbiologica Scandinavica. Section A, Pathology. 1980 ; Vol. 88, No. 3. pp. 175-8.

Bibtex

@article{17c624105c8511dd8d9f000ea68e967b,
title = "Immunohistochemical demonstration of a hitherto undescribed localization of hemoglobin A and F in endodermal cells of normal human yolk sac and endodermal sinus tumor.",
abstract = "In this study of 4 human yolk sacs, the presence of hemoglobin A and F (HbA and HbF) is demonstrated for the first time in epithelial cells (type 1) and erythroid-like cells (type 2) in the endodermal layer by immunoperoxidase technique. Our findings strongly support the hypothesis previously proposed that the red blood cells formed in the yolk sac are of endodermal origin. Tumor with yolk sac differentiation (8 endodermal sinus tumors and 1 embryonal carcinoma with vitelline areas) similarly showed HbA and HbF localisation in endodermal cells. None of 59 germ cell tumors of other types contained these hemoglobins in the neoplastic cells.",
author = "R Albrechtsen and U Wewer and Wimberley, {P D}",
note = "Keywords: Endoderm; Female; Fetal Hemoglobin; Hemoglobin A; Humans; Immunoenzyme Techniques; Male; Mesonephroma; Ovarian Neoplasms; Pregnancy; Testicular Neoplasms; Yolk Sac",
year = "1980",
language = "English",
volume = "88",
pages = "175--8",
journal = "Acta Pathologica et Microbiologica Scandinavica - Section A Pathology",
issn = "0365-4184",
publisher = "Munksgaard International Publishers",
number = "3",

}

RIS

TY - JOUR

T1 - Immunohistochemical demonstration of a hitherto undescribed localization of hemoglobin A and F in endodermal cells of normal human yolk sac and endodermal sinus tumor.

AU - Albrechtsen, R

AU - Wewer, U

AU - Wimberley, P D

N1 - Keywords: Endoderm; Female; Fetal Hemoglobin; Hemoglobin A; Humans; Immunoenzyme Techniques; Male; Mesonephroma; Ovarian Neoplasms; Pregnancy; Testicular Neoplasms; Yolk Sac

PY - 1980

Y1 - 1980

N2 - In this study of 4 human yolk sacs, the presence of hemoglobin A and F (HbA and HbF) is demonstrated for the first time in epithelial cells (type 1) and erythroid-like cells (type 2) in the endodermal layer by immunoperoxidase technique. Our findings strongly support the hypothesis previously proposed that the red blood cells formed in the yolk sac are of endodermal origin. Tumor with yolk sac differentiation (8 endodermal sinus tumors and 1 embryonal carcinoma with vitelline areas) similarly showed HbA and HbF localisation in endodermal cells. None of 59 germ cell tumors of other types contained these hemoglobins in the neoplastic cells.

AB - In this study of 4 human yolk sacs, the presence of hemoglobin A and F (HbA and HbF) is demonstrated for the first time in epithelial cells (type 1) and erythroid-like cells (type 2) in the endodermal layer by immunoperoxidase technique. Our findings strongly support the hypothesis previously proposed that the red blood cells formed in the yolk sac are of endodermal origin. Tumor with yolk sac differentiation (8 endodermal sinus tumors and 1 embryonal carcinoma with vitelline areas) similarly showed HbA and HbF localisation in endodermal cells. None of 59 germ cell tumors of other types contained these hemoglobins in the neoplastic cells.

M3 - Journal article

C2 - 6155756

VL - 88

SP - 175

EP - 178

JO - Acta Pathologica et Microbiologica Scandinavica - Section A Pathology

JF - Acta Pathologica et Microbiologica Scandinavica - Section A Pathology

SN - 0365-4184

IS - 3

ER -

ID: 5237298