Fansidar resistant falciparum malaria acquired in South East Asia
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Fansidar resistant falciparum malaria acquired in South East Asia. / Black, F.; Bygbjerg, I.; Effersoe, P.; Gomme, Grethe; Jepsen, S.; Axelgaard Jensen, G.
In: Transactions of the Royal Society of Tropical Medicine and Hygiene, Vol. 75, No. 5, 01.01.1981, p. 715-716.Research output: Contribution to journal › Letter › Research › peer-review
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TY - JOUR
T1 - Fansidar resistant falciparum malaria acquired in South East Asia
AU - Black, F.
AU - Bygbjerg, I.
AU - Effersoe, P.
AU - Gomme, Grethe
AU - Jepsen, S.
AU - Axelgaard Jensen, G.
PY - 1981/1/1
Y1 - 1981/1/1
N2 - A case of Plasmodium falciparum malaria resistant to Fansidar (sulphadoxine plus pyrimethamine) at a level corresponding to R III and resistant to chloroquine is reported. The infection was most certainly acquired in Malaysia, but diagnosed and treated in a non-malarious area. Normal resorption and elimination rates of the Fansidar components excludes cure failure due to abnormal drug fate in the host. P. falciparum parasites from the patient have been maintained in in vitro cultures. The patient was permanently cured with mefloquine.
AB - A case of Plasmodium falciparum malaria resistant to Fansidar (sulphadoxine plus pyrimethamine) at a level corresponding to R III and resistant to chloroquine is reported. The infection was most certainly acquired in Malaysia, but diagnosed and treated in a non-malarious area. Normal resorption and elimination rates of the Fansidar components excludes cure failure due to abnormal drug fate in the host. P. falciparum parasites from the patient have been maintained in in vitro cultures. The patient was permanently cured with mefloquine.
UR - http://www.scopus.com/inward/record.url?scp=0019776513&partnerID=8YFLogxK
U2 - 10.1016/0035-9203(81)90160-7
DO - 10.1016/0035-9203(81)90160-7
M3 - Letter
C2 - 7036431
AN - SCOPUS:0019776513
VL - 75
SP - 715
EP - 716
JO - Transactions of the Royal Society of Tropical Medicine and Hygiene
JF - Transactions of the Royal Society of Tropical Medicine and Hygiene
SN - 0035-9203
IS - 5
ER -
ID: 203862757