Do substance P and vasoactive intestinal polypeptide (VIP) play a role in the acute occlusive or chronic ischaemic vasodilation in man?

Research output: Contribution to journalJournal articleResearchpeer-review

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Do substance P and vasoactive intestinal polypeptide (VIP) play a role in the acute occlusive or chronic ischaemic vasodilation in man? / Henriksen, Jens Henrik Sahl; Bülow, J B; Schaffalitzky de Muckadell, O; Fahrenkrug, J.

In: Clinical physiology (Oxford, England), Vol. 6, No. 2, 1986, p. 163-70.

Research output: Contribution to journalJournal articleResearchpeer-review

Harvard

Henriksen, JHS, Bülow, JB, Schaffalitzky de Muckadell, O & Fahrenkrug, J 1986, 'Do substance P and vasoactive intestinal polypeptide (VIP) play a role in the acute occlusive or chronic ischaemic vasodilation in man?', Clinical physiology (Oxford, England), vol. 6, no. 2, pp. 163-70.

APA

Henriksen, J. H. S., Bülow, J. B., Schaffalitzky de Muckadell, O., & Fahrenkrug, J. (1986). Do substance P and vasoactive intestinal polypeptide (VIP) play a role in the acute occlusive or chronic ischaemic vasodilation in man? Clinical physiology (Oxford, England), 6(2), 163-70.

Vancouver

Henriksen JHS, Bülow JB, Schaffalitzky de Muckadell O, Fahrenkrug J. Do substance P and vasoactive intestinal polypeptide (VIP) play a role in the acute occlusive or chronic ischaemic vasodilation in man? Clinical physiology (Oxford, England). 1986;6(2):163-70.

Author

Henriksen, Jens Henrik Sahl ; Bülow, J B ; Schaffalitzky de Muckadell, O ; Fahrenkrug, J. / Do substance P and vasoactive intestinal polypeptide (VIP) play a role in the acute occlusive or chronic ischaemic vasodilation in man?. In: Clinical physiology (Oxford, England). 1986 ; Vol. 6, No. 2. pp. 163-70.

Bibtex

@article{26ebac2038cb11dfad7f000ea68e967b,
title = "Do substance P and vasoactive intestinal polypeptide (VIP) play a role in the acute occlusive or chronic ischaemic vasodilation in man?",
abstract = "The concentrations of substance P (SP) and vasoactive intestinal polypeptide (VIP) were determined in plasma in normal volunteers during acute occlusive ischaemia (n=5) and in patients with chronic ischaemia (n=5) due to obliterative arterial disease in the lower limbs. Venous SP, but not VIP, increased significantly in the early post-occlusive period in normal volunteers (P less than 0.02). In the patients no significant veno-arterial difference in plasma concentration of SP or VIP could be detected across normal or chronic ischaemic areas. The results may suggest a role for SP in the acute post-occlusive vasodilation and/or in the post-occlusive heat-pain sensation. A role for SP in chronic ischaemia could not be defined. Plasma VIP was unchanged in both acute and chronic ischaemia.",
author = "Henriksen, {Jens Henrik Sahl} and B{\"u}low, {J B} and {Schaffalitzky de Muckadell}, O and J Fahrenkrug",
note = "Keywords: Aged; Arterial Occlusive Diseases; Humans; Ischemia; Leg; Middle Aged; Substance P; Vasoactive Intestinal Peptide",
year = "1986",
language = "English",
volume = "6",
pages = "163--70",
journal = "Clinical Physiology",
issn = "0144-5979",
publisher = "Blackwell Science Ltd.",
number = "2",

}

RIS

TY - JOUR

T1 - Do substance P and vasoactive intestinal polypeptide (VIP) play a role in the acute occlusive or chronic ischaemic vasodilation in man?

AU - Henriksen, Jens Henrik Sahl

AU - Bülow, J B

AU - Schaffalitzky de Muckadell, O

AU - Fahrenkrug, J

N1 - Keywords: Aged; Arterial Occlusive Diseases; Humans; Ischemia; Leg; Middle Aged; Substance P; Vasoactive Intestinal Peptide

PY - 1986

Y1 - 1986

N2 - The concentrations of substance P (SP) and vasoactive intestinal polypeptide (VIP) were determined in plasma in normal volunteers during acute occlusive ischaemia (n=5) and in patients with chronic ischaemia (n=5) due to obliterative arterial disease in the lower limbs. Venous SP, but not VIP, increased significantly in the early post-occlusive period in normal volunteers (P less than 0.02). In the patients no significant veno-arterial difference in plasma concentration of SP or VIP could be detected across normal or chronic ischaemic areas. The results may suggest a role for SP in the acute post-occlusive vasodilation and/or in the post-occlusive heat-pain sensation. A role for SP in chronic ischaemia could not be defined. Plasma VIP was unchanged in both acute and chronic ischaemia.

AB - The concentrations of substance P (SP) and vasoactive intestinal polypeptide (VIP) were determined in plasma in normal volunteers during acute occlusive ischaemia (n=5) and in patients with chronic ischaemia (n=5) due to obliterative arterial disease in the lower limbs. Venous SP, but not VIP, increased significantly in the early post-occlusive period in normal volunteers (P less than 0.02). In the patients no significant veno-arterial difference in plasma concentration of SP or VIP could be detected across normal or chronic ischaemic areas. The results may suggest a role for SP in the acute post-occlusive vasodilation and/or in the post-occlusive heat-pain sensation. A role for SP in chronic ischaemia could not be defined. Plasma VIP was unchanged in both acute and chronic ischaemia.

M3 - Journal article

C2 - 2420506

VL - 6

SP - 163

EP - 170

JO - Clinical Physiology

JF - Clinical Physiology

SN - 0144-5979

IS - 2

ER -

ID: 18838199