CNN-based fully automatic mitral valve extraction using CT images and existence probability maps

Research output: Contribution to journalJournal articleResearchpeer-review

  • Yukiteru Masuda
  • Ryo Ishikawa
  • Toru Tanaka
  • Gakuto Aoyama
  • Keitaro Kawashima
  • James V. Chapman
  • Masahiko Asami
  • Michael Huy Cuong Pham
  • Kofoed, Klaus Fuglsang
  • Takuya Sakaguchi
  • Kiyohide Satoh

Objective. Accurate extraction of mitral valve shape from clinical tomographic images acquired in patients has proven useful for planning surgical and interventional mitral valve treatments. However, manual extraction of the mitral valve shape is laborious, and the existing automatic extraction methods have not been sufficiently accurate. In this paper, we propose a fully automated method of extracting mitral valve shape from computed tomography (CT) images for the all phases of the cardiac cycle. Approach. This method extracts the mitral valve shape based on DenseNet using both the original CT image and the existence probability maps of the mitral valve area inferred by U-Net as input. A total of 1585 CT images from 204 patients with various cardiac diseases including mitral regurgitation were collected and manually annotated for mitral valve region. The proposed method was trained and evaluated by 10-fold cross validation using the collected data and was compared with the method without the existence probability maps. Main results. The mean error of shape extraction error in the proposed method is 0.88 mm, which is an improvement of 0.32 mm compared with the method without the existence probability maps. Significance. We present a novel fully automatic mitral valve extraction method from input to output for all phases of 4D CT images. We suggest that the accuracy of mitral valve shape extraction is improved by using existence probability maps.

Original languageEnglish
Article number035001
JournalPhysics in Medicine and Biology
Volume69
Issue number3
Number of pages12
ISSN0031-9155
DOIs
Publication statusPublished - 2024

Bibliographical note

Publisher Copyright:
© 2024 Institute of Physics and Engineering in Medicine.

    Research areas

  • computed tomography, machine learning, mitral valve, point cloud, shape reconstruction

ID: 380216233