Ausencia de relación entre el genotipo y la virulencia en especies de Candida

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Standard

Ausencia de relación entre el genotipo y la virulencia en especies de Candida. / Díaz-García, Judith; Arendrup, Maiken C.; Cantón, Rafael; García-Rodríguez, Julio; de la Pedrosa, Elia Gómez García; Parisi, Gabriella; Pemán, Javier; Posteraro, Brunella; Sanguinetti, Maurizio; Da Matta, Daniel Archimedes; Colombo, Arnaldo L.; Muñoz, Patricia; Sánchez-Carrillo, Carlos; Guinea, Jesús; Escribano, Pilar.

In: Revista Iberoamericana de Micologia, Vol. 38, No. 1, 2021, p. 9-11.

Research output: Contribution to journal › Journal article › Research › peer-review

Harvard

Díaz-García, J, Arendrup, MC, Cantón, R, García-Rodríguez, J, de la Pedrosa, EGG, Parisi, G, Pemán, J, Posteraro, B, Sanguinetti, M, Da Matta, DA, Colombo, AL, Muñoz, P, Sánchez-Carrillo, C, Guinea, J & Escribano, P 2021, 'Ausencia de relación entre el genotipo y la virulencia en especies de Candida', Revista Iberoamericana de Micologia, vol. 38, no. 1, pp. 9-11. https://doi.org/10.1016/j.riam.2020.10.002

APA

Díaz-García, J., Arendrup, M. C., Cantón, R., García-Rodríguez, J., de la Pedrosa, E. G. G., Parisi, G., Pemán, J., Posteraro, B., Sanguinetti, M., Da Matta, D. A., Colombo, A. L., Muñoz, P., Sánchez-Carrillo, C., Guinea, J., & Escribano, P. (2021). Ausencia de relación entre el genotipo y la virulencia en especies de Candida. Revista Iberoamericana de Micologia, 38(1), 9-11. https://doi.org/10.1016/j.riam.2020.10.002

Vancouver

Díaz-García J, Arendrup MC, Cantón R, García-Rodríguez J, de la Pedrosa EGG, Parisi G et al. Ausencia de relación entre el genotipo y la virulencia en especies de Candida. Revista Iberoamericana de Micologia. 2021;38(1):9-11. https://doi.org/10.1016/j.riam.2020.10.002

Author

Díaz-García, Judith ; Arendrup, Maiken C. ; Cantón, Rafael ; García-Rodríguez, Julio ; de la Pedrosa, Elia Gómez García ; Parisi, Gabriella ; Pemán, Javier ; Posteraro, Brunella ; Sanguinetti, Maurizio ; Da Matta, Daniel Archimedes ; Colombo, Arnaldo L. ; Muñoz, Patricia ; Sánchez-Carrillo, Carlos ; Guinea, Jesús ; Escribano, Pilar. / Ausencia de relación entre el genotipo y la virulencia en especies de Candida. In: Revista Iberoamericana de Micologia. 2021 ; Vol. 38, No. 1. pp. 9-11.

Bibtex

@article{96e72b8069a04aee99b8d6682cdbf725,
title = "Ausencia de relaci{\'o}n entre el genotipo y la virulencia en especies de Candida",
abstract = "Background: The virulence of isolates among different Candida species causing candidemia may play a role in the prognosis of the patients. Furthermore, the potential relationship between genotype and virulence is still unclear and need to be further studied. Aims: We aim to assess the relationship between genotype and virulence in Candida species using a Galleria mellonella larvae infection model. Methods: One hundred and ninety-four isolates from 68 clusters (Candida albicans, 114/41; Candida parapsilosis, 74/24; Candida tropicalis, 6/3) were compared against the same number of each species singleton genotypes in terms of survival of G. mellonella larvae. Results: The median of survival and the IQR ranges of clusters and singleton were as follows: C. albicans (2 days, IQR 1.5–2 vs. 2 days, IQR 1–2.25), C. parapsilosis (2 days, IQR 1.5–2.6 vs. 2 days, IQR 2–3.3), and C. tropicalis (1 day, IQR 1–3.5 vs. 2 days, IQR 2–3.5; p < 0.05). High intra-cluster variability in terms of median of survival was found regardless the species. Conclusions: No relationship between genotype and virulence in Candida was observed with the G. mellonella model.",
keywords = "Candida albicans, Candida parapsilosis, Candida tropicalis, Galleria mellonella, Genotyping, Virulence",
author = "Judith D{\'i}az-Garc{\'i}a and Arendrup, {Maiken C.} and Rafael Cant{\'o}n and Julio Garc{\'i}a-Rodr{\'i}guez and {de la Pedrosa}, {Elia G{\'o}mez Garc{\'i}a} and Gabriella Parisi and Javier Pem{\'a}n and Brunella Posteraro and Maurizio Sanguinetti and {Da Matta}, {Daniel Archimedes} and Colombo, {Arnaldo L.} and Patricia Mu{\~n}oz and Carlos S{\'a}nchez-Carrillo and Jes{\'u}s Guinea and Pilar Escribano",
year = "2021",
doi = "10.1016/j.riam.2020.10.002",
language = "Spansk",
volume = "38",
pages = "9--11",
journal = "Revista Iberoamericana de Micologia",
issn = "1130-1406",
publisher = "Elsevier Doyma",
number = "1",

}

RIS

TY - JOUR

T1 - Ausencia de relación entre el genotipo y la virulencia en especies de Candida

AU - Díaz-García, Judith

AU - Arendrup, Maiken C.

AU - Cantón, Rafael

AU - García-Rodríguez, Julio

AU - de la Pedrosa, Elia Gómez García

AU - Parisi, Gabriella

AU - Pemán, Javier

AU - Posteraro, Brunella

AU - Sanguinetti, Maurizio

AU - Da Matta, Daniel Archimedes

AU - Colombo, Arnaldo L.

AU - Muñoz, Patricia

AU - Sánchez-Carrillo, Carlos

AU - Guinea, Jesús

AU - Escribano, Pilar

PY - 2021

Y1 - 2021

N2 - Background: The virulence of isolates among different Candida species causing candidemia may play a role in the prognosis of the patients. Furthermore, the potential relationship between genotype and virulence is still unclear and need to be further studied. Aims: We aim to assess the relationship between genotype and virulence in Candida species using a Galleria mellonella larvae infection model. Methods: One hundred and ninety-four isolates from 68 clusters (Candida albicans, 114/41; Candida parapsilosis, 74/24; Candida tropicalis, 6/3) were compared against the same number of each species singleton genotypes in terms of survival of G. mellonella larvae. Results: The median of survival and the IQR ranges of clusters and singleton were as follows: C. albicans (2 days, IQR 1.5–2 vs. 2 days, IQR 1–2.25), C. parapsilosis (2 days, IQR 1.5–2.6 vs. 2 days, IQR 2–3.3), and C. tropicalis (1 day, IQR 1–3.5 vs. 2 days, IQR 2–3.5; p < 0.05). High intra-cluster variability in terms of median of survival was found regardless the species. Conclusions: No relationship between genotype and virulence in Candida was observed with the G. mellonella model.

AB - Background: The virulence of isolates among different Candida species causing candidemia may play a role in the prognosis of the patients. Furthermore, the potential relationship between genotype and virulence is still unclear and need to be further studied. Aims: We aim to assess the relationship between genotype and virulence in Candida species using a Galleria mellonella larvae infection model. Methods: One hundred and ninety-four isolates from 68 clusters (Candida albicans, 114/41; Candida parapsilosis, 74/24; Candida tropicalis, 6/3) were compared against the same number of each species singleton genotypes in terms of survival of G. mellonella larvae. Results: The median of survival and the IQR ranges of clusters and singleton were as follows: C. albicans (2 days, IQR 1.5–2 vs. 2 days, IQR 1–2.25), C. parapsilosis (2 days, IQR 1.5–2.6 vs. 2 days, IQR 2–3.3), and C. tropicalis (1 day, IQR 1–3.5 vs. 2 days, IQR 2–3.5; p < 0.05). High intra-cluster variability in terms of median of survival was found regardless the species. Conclusions: No relationship between genotype and virulence in Candida was observed with the G. mellonella model.

KW - Candida albicans

KW - Candida parapsilosis

KW - Candida tropicalis

KW - Galleria mellonella

KW - Genotyping

KW - Virulence

U2 - 10.1016/j.riam.2020.10.002

DO - 10.1016/j.riam.2020.10.002

M3 - Tidsskriftartikel

C2 - 33358083

AN - SCOPUS:85098653166

VL - 38

SP - 9

EP - 11

JO - Revista Iberoamericana de Micologia

JF - Revista Iberoamericana de Micologia

SN - 1130-1406

IS - 1

ER -

ID: 255458980