An imidazoline compound completely counteracts interleukin-1[beta] toxic effects to rat pancreatic islet [beta] cells
Research output: Contribution to journal › Journal article › Research › peer-review
In vitro studies have demonstrated that interleukin (IL)-1beta decreases insulin and DNA contents in pancreatic islet beta cells, causing structural damage, that it is toxic to cultured human islet beta cells and that it is able to induce apoptosis in these cells.
| Original language | English |
|---|---|
| Journal | Molecular Medicine |
| Volume | 8 |
| Issue number | 9 |
| Pages (from-to) | 536-45 |
| Number of pages | 10 |
| ISSN | 1076-1551 |
| Publication status | Published - 1 Sep 2002 |
ID: 34101966