An imidazoline compound completely counteracts interleukin-1[beta] toxic effects to rat pancreatic islet [beta] cells
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An imidazoline compound completely counteracts interleukin-1[beta] toxic effects to rat pancreatic islet [beta] cells. / Papaccio, Gianpaolo; Nicoletti, Ferdinando; Pisanti, Francesco A; Galdieri, Michela; Bendtzen, Klaus.
In: Molecular Medicine, Vol. 8, No. 9, 01.09.2002, p. 536-45.Research output: Contribution to journal › Journal article › Research › peer-review
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TY - JOUR
T1 - An imidazoline compound completely counteracts interleukin-1[beta] toxic effects to rat pancreatic islet [beta] cells
AU - Papaccio, Gianpaolo
AU - Nicoletti, Ferdinando
AU - Pisanti, Francesco A
AU - Galdieri, Michela
AU - Bendtzen, Klaus
PY - 2002/9/1
Y1 - 2002/9/1
N2 - In vitro studies have demonstrated that interleukin (IL)-1beta decreases insulin and DNA contents in pancreatic islet beta cells, causing structural damage, that it is toxic to cultured human islet beta cells and that it is able to induce apoptosis in these cells.
AB - In vitro studies have demonstrated that interleukin (IL)-1beta decreases insulin and DNA contents in pancreatic islet beta cells, causing structural damage, that it is toxic to cultured human islet beta cells and that it is able to induce apoptosis in these cells.
M3 - Journal article
VL - 8
SP - 536
EP - 545
JO - Molecular Medicine
JF - Molecular Medicine
SN - 1076-1551
IS - 9
ER -
ID: 34101966