A letter to the editor: The effects of alcohol use on brain glutamate in first episode psychosis

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A letter to the editor : The effects of alcohol use on brain glutamate in first episode psychosis. / King, Bridget; Kempton, Matthew J.; Broberg, Brian V.; Merritt, Kate; Barker, Gareth J.; Lythgoe, David J.; Perez-Iglesias, Rocio; Baandrup, Lone; Düring, Signe W.; Stone, James M.; Rostrup, Egill; Sommer, Iris E.; Glenthøj, Birte; Kahn, René S.; Dazzan, Paola; McGuire, Philip K.; Egerton, Alice.

In: Schizophrenia Research, Vol. 266, 2024, p. 234-236.

Research output: Contribution to journalLetterResearchpeer-review

Harvard

King, B, Kempton, MJ, Broberg, BV, Merritt, K, Barker, GJ, Lythgoe, DJ, Perez-Iglesias, R, Baandrup, L, Düring, SW, Stone, JM, Rostrup, E, Sommer, IE, Glenthøj, B, Kahn, RS, Dazzan, P, McGuire, PK & Egerton, A 2024, 'A letter to the editor: The effects of alcohol use on brain glutamate in first episode psychosis', Schizophrenia Research, vol. 266, pp. 234-236. https://doi.org/10.1016/j.schres.2024.02.013

APA

King, B., Kempton, M. J., Broberg, B. V., Merritt, K., Barker, G. J., Lythgoe, D. J., Perez-Iglesias, R., Baandrup, L., Düring, S. W., Stone, J. M., Rostrup, E., Sommer, I. E., Glenthøj, B., Kahn, R. S., Dazzan, P., McGuire, P. K., & Egerton, A. (2024). A letter to the editor: The effects of alcohol use on brain glutamate in first episode psychosis. Schizophrenia Research, 266, 234-236. https://doi.org/10.1016/j.schres.2024.02.013

Vancouver

King B, Kempton MJ, Broberg BV, Merritt K, Barker GJ, Lythgoe DJ et al. A letter to the editor: The effects of alcohol use on brain glutamate in first episode psychosis. Schizophrenia Research. 2024;266:234-236. https://doi.org/10.1016/j.schres.2024.02.013

Author

King, Bridget ; Kempton, Matthew J. ; Broberg, Brian V. ; Merritt, Kate ; Barker, Gareth J. ; Lythgoe, David J. ; Perez-Iglesias, Rocio ; Baandrup, Lone ; Düring, Signe W. ; Stone, James M. ; Rostrup, Egill ; Sommer, Iris E. ; Glenthøj, Birte ; Kahn, René S. ; Dazzan, Paola ; McGuire, Philip K. ; Egerton, Alice. / A letter to the editor : The effects of alcohol use on brain glutamate in first episode psychosis. In: Schizophrenia Research. 2024 ; Vol. 266. pp. 234-236.

Bibtex

@article{0d984743f9f6468cbff4986e0eb7236d,
title = "A letter to the editor: The effects of alcohol use on brain glutamate in first episode psychosis",
abstract = "Alcohol use in schizophrenia is associated with poorer outcomes, such as increased suicidality and positive symptoms (Lv et al., 2023). Both alcohol use and psychosis have been independently associated with changes in brain glutamate levels. However, whether alcohol use impacts brain glutamate levels in people with psychosis is unknown. Potentially, overlapping glutamatergic pathophysiology could mean that, patients with schizophrenia are more vulnerable to the effects of alcohol.",
keywords = "H-MRS, Alcohol, Glutamate, Magnetic resonance spectroscopy, Psychosis",
author = "Bridget King and Kempton, {Matthew J.} and Broberg, {Brian V.} and Kate Merritt and Barker, {Gareth J.} and Lythgoe, {David J.} and Rocio Perez-Iglesias and Lone Baandrup and D{\"u}ring, {Signe W.} and Stone, {James M.} and Egill Rostrup and Sommer, {Iris E.} and Birte Glenth{\o}j and Kahn, {Ren{\'e} S.} and Paola Dazzan and McGuire, {Philip K.} and Alice Egerton",
note = "Funding Information: In the last 3 years, J.M.S. has been principal investigator or sub-investigator on studies sponsored by Takeda, Janssen and Lundbeck Plc. During study conduct and data collection, B.B was employed at Mental Health Services, Capital Region of Denmark, University of Copenhagen, Glostrup, Denmark. B.B is currently employed by H.Lundbeck A/S and has not been directly involved in the data analysis, but reviewed the manuscript. B.G has been the leader of a Lundbeck Foundation Centre of Excellence for Clinical Intervention and Neuropsychiatric Schizophrenia Research (CINS) (January 2009–December 2021), which was partially financed by an independent grant from the Lundbeck Foundation based on international review and partially financed by the Mental Health Services in the Capital Region of Denmark, the University of Copenhagen, and other foundations. All grants are the property of the Mental Health Services in the Capital Region of Denmark and administrated by them.",
year = "2024",
doi = "10.1016/j.schres.2024.02.013",
language = "English",
volume = "266",
pages = "234--236",
journal = "Schizophrenia Research",
issn = "0920-9964",
publisher = "Elsevier",

}

RIS

TY - JOUR

T1 - A letter to the editor

T2 - The effects of alcohol use on brain glutamate in first episode psychosis

AU - King, Bridget

AU - Kempton, Matthew J.

AU - Broberg, Brian V.

AU - Merritt, Kate

AU - Barker, Gareth J.

AU - Lythgoe, David J.

AU - Perez-Iglesias, Rocio

AU - Baandrup, Lone

AU - Düring, Signe W.

AU - Stone, James M.

AU - Rostrup, Egill

AU - Sommer, Iris E.

AU - Glenthøj, Birte

AU - Kahn, René S.

AU - Dazzan, Paola

AU - McGuire, Philip K.

AU - Egerton, Alice

N1 - Funding Information: In the last 3 years, J.M.S. has been principal investigator or sub-investigator on studies sponsored by Takeda, Janssen and Lundbeck Plc. During study conduct and data collection, B.B was employed at Mental Health Services, Capital Region of Denmark, University of Copenhagen, Glostrup, Denmark. B.B is currently employed by H.Lundbeck A/S and has not been directly involved in the data analysis, but reviewed the manuscript. B.G has been the leader of a Lundbeck Foundation Centre of Excellence for Clinical Intervention and Neuropsychiatric Schizophrenia Research (CINS) (January 2009–December 2021), which was partially financed by an independent grant from the Lundbeck Foundation based on international review and partially financed by the Mental Health Services in the Capital Region of Denmark, the University of Copenhagen, and other foundations. All grants are the property of the Mental Health Services in the Capital Region of Denmark and administrated by them.

PY - 2024

Y1 - 2024

N2 - Alcohol use in schizophrenia is associated with poorer outcomes, such as increased suicidality and positive symptoms (Lv et al., 2023). Both alcohol use and psychosis have been independently associated with changes in brain glutamate levels. However, whether alcohol use impacts brain glutamate levels in people with psychosis is unknown. Potentially, overlapping glutamatergic pathophysiology could mean that, patients with schizophrenia are more vulnerable to the effects of alcohol.

AB - Alcohol use in schizophrenia is associated with poorer outcomes, such as increased suicidality and positive symptoms (Lv et al., 2023). Both alcohol use and psychosis have been independently associated with changes in brain glutamate levels. However, whether alcohol use impacts brain glutamate levels in people with psychosis is unknown. Potentially, overlapping glutamatergic pathophysiology could mean that, patients with schizophrenia are more vulnerable to the effects of alcohol.

KW - H-MRS

KW - Alcohol

KW - Glutamate

KW - Magnetic resonance spectroscopy

KW - Psychosis

U2 - 10.1016/j.schres.2024.02.013

DO - 10.1016/j.schres.2024.02.013

M3 - Letter

C2 - 38430851

AN - SCOPUS:85186551254

VL - 266

SP - 234

EP - 236

JO - Schizophrenia Research

JF - Schizophrenia Research

SN - 0920-9964

ER -

ID: 385693468