15-hydroxyprostaglandin dehydrogenase activity in vitro in lung and kidney of essential fatty acid-deficient rats

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Standard

15-hydroxyprostaglandin dehydrogenase activity in vitro in lung and kidney of essential fatty acid-deficient rats. / Hansen, Harald S.; Toft, B.S.

In: BBA General Subjects, Vol. 529, No. 2, 01.01.1978, p. 230-236.

Research output: Contribution to journal › Journal article › Research › peer-review

Harvard

Hansen, HS & Toft, BS 1978, '15-hydroxyprostaglandin dehydrogenase activity in vitro in lung and kidney of essential fatty acid-deficient rats', BBA General Subjects, vol. 529, no. 2, pp. 230-236.

APA

Hansen, H. S., & Toft, B. S. (1978). 15-hydroxyprostaglandin dehydrogenase activity in vitro in lung and kidney of essential fatty acid-deficient rats. BBA General Subjects, 529(2), 230-236.

Vancouver

Hansen HS, Toft BS. 15-hydroxyprostaglandin dehydrogenase activity in vitro in lung and kidney of essential fatty acid-deficient rats. BBA General Subjects. 1978 Jan 1;529(2):230-236.

Author

Hansen, Harald S. ; Toft, B.S. / 15-hydroxyprostaglandin dehydrogenase activity in vitro in lung and kidney of essential fatty acid-deficient rats. In: BBA General Subjects. 1978 ; Vol. 529, No. 2. pp. 230-236.

Bibtex

@article{62c4b097ec9a4c3ea82b4910b74495b0,
title = "15-hydroxyprostaglandin dehydrogenase activity in vitro in lung and kidney of essential fatty acid-deficient rats",
abstract = "Weanling rats were fed for 6 months on a diet deficient in essential fatty acids: either fat-free, or with 28% (w/w) partially hydrogenated fish oil. Control rats were fed a diet with 28% (w/w) arachis oil for 6 months. 15-Hydroxyprostaglandin dehydrogenase activity was determined as initial rates of formation of H-labelled 15-keto-dihydro-prostaglandin E plus 15-keto-prostaglandin E in high speed supernatants of lung and kidney from each of the groups of rats. Dehydrogenase activity (expressed as either pmol/min per mg soluble protein, or as nmol/min per g tissue) was decreased 30-40% in the lungs of the two groups on diets deficient in essential fatty acids as compared to the control group. No difference was observed in dehydrogenase activity in the kidneys. The dehydrogenase may be of importance for the regulation of the level of endogenous prostaglandins and, thus, a decrease in activity could result in a slower turnover of prostaglandins.",
author = "Hansen, {Harald S.} and B.S. Toft",
year = "1978",
month = jan,
day = "1",
language = "English",
volume = "529",
pages = "230--236",
journal = "B B A - General Subjects",
issn = "0304-4165",
publisher = "Elsevier",
number = "2",

}

RIS

TY - JOUR

T1 - 15-hydroxyprostaglandin dehydrogenase activity in vitro in lung and kidney of essential fatty acid-deficient rats

AU - Hansen, Harald S.

AU - Toft, B.S.

PY - 1978/1/1

Y1 - 1978/1/1

N2 - Weanling rats were fed for 6 months on a diet deficient in essential fatty acids: either fat-free, or with 28% (w/w) partially hydrogenated fish oil. Control rats were fed a diet with 28% (w/w) arachis oil for 6 months. 15-Hydroxyprostaglandin dehydrogenase activity was determined as initial rates of formation of H-labelled 15-keto-dihydro-prostaglandin E plus 15-keto-prostaglandin E in high speed supernatants of lung and kidney from each of the groups of rats. Dehydrogenase activity (expressed as either pmol/min per mg soluble protein, or as nmol/min per g tissue) was decreased 30-40% in the lungs of the two groups on diets deficient in essential fatty acids as compared to the control group. No difference was observed in dehydrogenase activity in the kidneys. The dehydrogenase may be of importance for the regulation of the level of endogenous prostaglandins and, thus, a decrease in activity could result in a slower turnover of prostaglandins.

AB - Weanling rats were fed for 6 months on a diet deficient in essential fatty acids: either fat-free, or with 28% (w/w) partially hydrogenated fish oil. Control rats were fed a diet with 28% (w/w) arachis oil for 6 months. 15-Hydroxyprostaglandin dehydrogenase activity was determined as initial rates of formation of H-labelled 15-keto-dihydro-prostaglandin E plus 15-keto-prostaglandin E in high speed supernatants of lung and kidney from each of the groups of rats. Dehydrogenase activity (expressed as either pmol/min per mg soluble protein, or as nmol/min per g tissue) was decreased 30-40% in the lungs of the two groups on diets deficient in essential fatty acids as compared to the control group. No difference was observed in dehydrogenase activity in the kidneys. The dehydrogenase may be of importance for the regulation of the level of endogenous prostaglandins and, thus, a decrease in activity could result in a slower turnover of prostaglandins.

UR - http://www.scopus.com/inward/record.url?scp=0018200354&partnerID=8YFLogxK

M3 - Journal article

AN - SCOPUS:0018200354

VL - 529

SP - 230

EP - 236

JO - B B A - General Subjects

JF - B B A - General Subjects

SN - 0304-4165

IS - 2

ER -

ID: 45561411