11beta-hydroxysteroid dehydrogenase type 1 in adipose tissue and prospective changes in body weight and insulin resistance

Research output: Contribution to journalJournal articleResearchpeer-review

  • Juraj Koska
  • Barbora de Courten
  • Deborah J Wake
  • Saraswathy Nair
  • Brian R Walker
  • Joy C Bunt
  • Paska A Permana
  • Robert S Lindsay
  • P Antonio Tataranni
Increased mRNA and activity levels of 11beta-hydroxysteroid dehydrogenase type 1 (11betaHSD1) in human adipose tissue (AT) are associated with obesity and insulin resistance. The aim of our study was to investigate whether 11betaHSD1 expression or activity in abdominal subcutaneous AT of non-diabetic subjects are associated with subsequent changes in body weight and insulin resistance [homeostasis model assessment of insulin resistance (HOMA-IR)].
Original languageEnglish
JournalObesity
Volume14
Issue number9
Pages (from-to)1515-22
Number of pages8
ISSN1930-7381
DOIs
Publication statusPublished - 1 Sep 2006

    Research areas

  • 11-beta-Hydroxysteroid Dehydrogenase Type 1, Adipocytes, Adolescent, Adult, Body Weight, Female, Humans, Indians, North American, Insulin Resistance, Male, Middle Aged, Prospective Studies, RNA, Messenger, Subcutaneous Fat, Abdominal

ID: 33925470