A low-gluten diet induces changes in the intestinal microbiome of healthy Danish adults
Research output: Contribution to journal › Journal article › Research › peer-review
Documents
- Hansen et al_Nature Communications_2018_Vol 9_4630
Final published version, 1.28 MB, PDF document
Adherence to a low-gluten diet has become increasingly common in parts of the general population. However, the effects of reducing gluten-rich food items including wheat, barley and rye cereals in healthy adults are unclear. Here, we undertook a randomised, controlled, cross-over trial involving 60 middle-aged Danish adults without known disorders with two 8-week interventions comparing a low-gluten diet (2 g gluten per day) and a high-gluten diet (18 g gluten per day), separated by a washout period of at least six weeks with habitual diet (12 g gluten per day). We find that, in comparison with a high-gluten diet, a low-gluten diet induces moderate changes in the intestinal microbiome, reduces fasting and postprandial hydrogen exhalation, and leads to improvements in self-reported bloating. These observations suggest that most of the effects of a low-gluten diet in non-coeliac adults may be driven by qualitative changes in dietary fibres.
Original language | English |
---|---|
Article number | 4630 |
Journal | Nature Communications |
Volume | 9 |
Number of pages | 13 |
ISSN | 2041-1723 |
DOIs | |
Publication status | Published - 2018 |
- Faculty of Science - Low-gluten diet, Intestinal microbiome, Dietary fibres
Research areas
Number of downloads are based on statistics from Google Scholar and www.ku.dk
No data available
ID: 208869531