WhichCyp: prediction of cytochromes P450 inhibition

Research output: Contribution to journal › Journal article › Research › peer-review

Standard

WhichCyp : prediction of cytochromes P450 inhibition. / Rostkowski, Michal; Spjuth, Ola; Rydberg, Patrik.

In: Bioinformatics, Vol. 29, No. 16, 2013, p. 2051-2052.

Research output: Contribution to journal › Journal article › Research › peer-review

Harvard

Rostkowski, M, Spjuth, O & Rydberg, P 2013, 'WhichCyp: prediction of cytochromes P450 inhibition', Bioinformatics, vol. 29, no. 16, pp. 2051-2052. https://doi.org/10.1093/bioinformatics/btt325

APA

Rostkowski, M., Spjuth, O., & Rydberg, P. (2013). WhichCyp: prediction of cytochromes P450 inhibition. Bioinformatics, 29(16), 2051-2052. https://doi.org/10.1093/bioinformatics/btt325

Vancouver

Rostkowski M, Spjuth O, Rydberg P. WhichCyp: prediction of cytochromes P450 inhibition. Bioinformatics. 2013;29(16):2051-2052. https://doi.org/10.1093/bioinformatics/btt325

Author

Rostkowski, Michal ; Spjuth, Ola ; Rydberg, Patrik. / WhichCyp : prediction of cytochromes P450 inhibition. In: Bioinformatics. 2013 ; Vol. 29, No. 16. pp. 2051-2052.

Bibtex

@article{33792f4221c044a587fd07ed4cf64fb4,
title = "WhichCyp: prediction of cytochromes P450 inhibition",
abstract = "SUMMARY: In this work we present WhichCyp, a tool for prediction of which cytochromes P450 isoforms (among 1A2, 2C9, 2C19, 2D6 and 3A4) a given molecule is likely to inhibit. The models are built from experimental high-throughput data using support vector machines and molecular signatures. AVAILABILITY: The WhichCyp server is freely available for use on the web at https://drug.ku.dk/whichcyp, where the WhichCyp Java program and source code is also available for download. CONTACT: pry@sund.ku.dk SUPPLEMENTARY INFORMATION: Supplementary data are available at Bioinformatics online.",
author = "Michal Rostkowski and Ola Spjuth and Patrik Rydberg",
year = "2013",
doi = "10.1093/bioinformatics/btt325",
language = "English",
volume = "29",
pages = "2051--2052",
journal = "Computer Applications in the Biosciences",
issn = "1471-2105",
publisher = "Oxford University Press",
number = "16",

}

RIS

TY - JOUR

T1 - WhichCyp

T2 - prediction of cytochromes P450 inhibition

AU - Rostkowski, Michal

AU - Spjuth, Ola

AU - Rydberg, Patrik

PY - 2013

Y1 - 2013

N2 - SUMMARY: In this work we present WhichCyp, a tool for prediction of which cytochromes P450 isoforms (among 1A2, 2C9, 2C19, 2D6 and 3A4) a given molecule is likely to inhibit. The models are built from experimental high-throughput data using support vector machines and molecular signatures. AVAILABILITY: The WhichCyp server is freely available for use on the web at https://drug.ku.dk/whichcyp, where the WhichCyp Java program and source code is also available for download. CONTACT: pry@sund.ku.dk SUPPLEMENTARY INFORMATION: Supplementary data are available at Bioinformatics online.

AB - SUMMARY: In this work we present WhichCyp, a tool for prediction of which cytochromes P450 isoforms (among 1A2, 2C9, 2C19, 2D6 and 3A4) a given molecule is likely to inhibit. The models are built from experimental high-throughput data using support vector machines and molecular signatures. AVAILABILITY: The WhichCyp server is freely available for use on the web at https://drug.ku.dk/whichcyp, where the WhichCyp Java program and source code is also available for download. CONTACT: pry@sund.ku.dk SUPPLEMENTARY INFORMATION: Supplementary data are available at Bioinformatics online.

U2 - 10.1093/bioinformatics/btt325

DO - 10.1093/bioinformatics/btt325

M3 - Journal article

C2 - 23740742

VL - 29

SP - 2051

EP - 2052

JO - Computer Applications in the Biosciences

JF - Computer Applications in the Biosciences

SN - 1471-2105

IS - 16

ER -

ID: 46087803