The role of Cockayne Syndrome group B (CSB) protein in base excision repair and aging

Research output: Contribution to journal › Journal article › Research › peer-review

Standard

The role of Cockayne Syndrome group B (CSB) protein in base excision repair and aging. / Stevnsner, Tinna; Muftuoglu, Meltem; Aamann, Maria Diget; Bohr, Vilhelm A.

In: Mechanisms of Ageing and Development, Vol. 129, No. 7-8, 2008, p. 441-8.

Research output: Contribution to journal › Journal article › Research › peer-review

Harvard

Stevnsner, T, Muftuoglu, M, Aamann, MD & Bohr, VA 2008, 'The role of Cockayne Syndrome group B (CSB) protein in base excision repair and aging', Mechanisms of Ageing and Development, vol. 129, no. 7-8, pp. 441-8. https://doi.org/10.1016/j.mad.2008.04.009

APA

Stevnsner, T., Muftuoglu, M., Aamann, M. D., & Bohr, V. A. (2008). The role of Cockayne Syndrome group B (CSB) protein in base excision repair and aging. Mechanisms of Ageing and Development, 129(7-8), 441-8. https://doi.org/10.1016/j.mad.2008.04.009

Vancouver

Stevnsner T, Muftuoglu M, Aamann MD, Bohr VA. The role of Cockayne Syndrome group B (CSB) protein in base excision repair and aging. Mechanisms of Ageing and Development. 2008;129(7-8):441-8. https://doi.org/10.1016/j.mad.2008.04.009

Author

Stevnsner, Tinna ; Muftuoglu, Meltem ; Aamann, Maria Diget ; Bohr, Vilhelm A. / The role of Cockayne Syndrome group B (CSB) protein in base excision repair and aging. In: Mechanisms of Ageing and Development. 2008 ; Vol. 129, No. 7-8. pp. 441-8.

Bibtex

@article{c5d65900664111de8bc9000ea68e967b,
title = "The role of Cockayne Syndrome group B (CSB) protein in base excision repair and aging",
abstract = "Cockayne Syndrome (CS) is a rare human genetic disorder characterized by progressive multisystem degeneration and segmental premature aging. The CS complementation group B (CSB) protein is engaged in transcription coupled and global nucleotide excision repair, base excision repair and general transcription. However, the precise molecular function of the CSB protein is still unclear. In the current review we discuss the involvement of CSB in some of these processes, with focus on the role of CSB in repair of oxidative damage, as deficiencies in the repair of these lesions may be an important aspect of the premature aging phenotype of CS.",
author = "Tinna Stevnsner and Meltem Muftuoglu and Aamann, {Maria Diget} and Bohr, {Vilhelm A}",
note = "Keywords: Aging; Aging, Premature; Chromatin; Cockayne Syndrome; DNA Damage; DNA Helicases; DNA Repair; DNA Repair Enzymes; Humans",
year = "2008",
doi = "10.1016/j.mad.2008.04.009",
language = "English",
volume = "129",
pages = "441--8",
journal = "Mechanisms of Ageing and Development",
issn = "0047-6374",
publisher = "Elsevier Ireland Ltd",
number = "7-8",

}

RIS

TY - JOUR

T1 - The role of Cockayne Syndrome group B (CSB) protein in base excision repair and aging

AU - Stevnsner, Tinna

AU - Muftuoglu, Meltem

AU - Aamann, Maria Diget

AU - Bohr, Vilhelm A

N1 - Keywords: Aging; Aging, Premature; Chromatin; Cockayne Syndrome; DNA Damage; DNA Helicases; DNA Repair; DNA Repair Enzymes; Humans

PY - 2008

Y1 - 2008

N2 - Cockayne Syndrome (CS) is a rare human genetic disorder characterized by progressive multisystem degeneration and segmental premature aging. The CS complementation group B (CSB) protein is engaged in transcription coupled and global nucleotide excision repair, base excision repair and general transcription. However, the precise molecular function of the CSB protein is still unclear. In the current review we discuss the involvement of CSB in some of these processes, with focus on the role of CSB in repair of oxidative damage, as deficiencies in the repair of these lesions may be an important aspect of the premature aging phenotype of CS.

AB - Cockayne Syndrome (CS) is a rare human genetic disorder characterized by progressive multisystem degeneration and segmental premature aging. The CS complementation group B (CSB) protein is engaged in transcription coupled and global nucleotide excision repair, base excision repair and general transcription. However, the precise molecular function of the CSB protein is still unclear. In the current review we discuss the involvement of CSB in some of these processes, with focus on the role of CSB in repair of oxidative damage, as deficiencies in the repair of these lesions may be an important aspect of the premature aging phenotype of CS.

U2 - 10.1016/j.mad.2008.04.009

DO - 10.1016/j.mad.2008.04.009

M3 - Journal article

C2 - 18541289

VL - 129

SP - 441

EP - 448

JO - Mechanisms of Ageing and Development

JF - Mechanisms of Ageing and Development

SN - 0047-6374

IS - 7-8

ER -

ID: 12899045