South African plants used in traditional medicine to treat epilepsy have an antagonistic effect on NMDA receptor currents

Research output: Contribution to journalJournal articleResearchpeer-review

  • Carla Marchetti
  • Paola Gavazzo
  • Gary Ivan Stafford
  • Johannes Van Staden
Several Searsia species (Anacardiaceae), including Searsia dentata and Searsia pyroides, are used in South Africa traditional medicine to treat epilepsy. Ethanol leaf extracts of these plants have been shown to act as possible antagonists of N-methyl-d-aspartate (NMDA)-type glutamate receptors.
Original languageEnglish
JournalJournal of Ethnopharmacology
Volume137
Issue number1
Pages (from-to)382-388
Number of pages7
ISSN0378-8741
DOIs
Publication statusPublished - 1 Sep 2011
Externally publishedYes

ID: 34210322