Solid-phase synthesis of 3-amino-2-pyrazolines
Research output: Contribution to journal › Journal article › Research › peer-review
The development of a solid-phase synthesis of 3-amino-2-pyrazolines is described. Conjugate addition of hydrazines to α,β-unsaturated nitriles followed by cyclization yields 3-amino-2-pyrazolines. Acylation or sulfonation of the free amino-group yields a 24 member library of 3-amino-2- pyrazolines.
| Original language | English |
|---|---|
| Journal | Tetrahedron Letters |
| Volume | 39 |
| Issue number | 32 |
| Pages (from-to) | 5845-5848 |
| Number of pages | 4 |
| ISSN | 0040-4039 |
| DOIs | |
| Publication status | Published - 6 Aug 1998 |
ID: 131118211