Should the indications for prenatal chromosome analysis be changed?
Research output: Contribution to journal › Journal article › Research › peer-review
Amniocentesis for chromosome analysis was performed in 1086 pergnant women, 739 of whom had an increased risk of giving birth to a child with chromosome abnormalities. Such abnormalities were found in almost identical proportions among the fetuses with an increased risk (1.2%) and among those with no increased risk (1.4%). Findings in several other studies seem to confirm that there is no significant difference between the risk groups in the proportion of abnormalities found. This suggests that our current risk groups may not be the right ones, but a much larger study is needed to confirm this.
Original language | English |
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Journal | British medical journal |
Volume | 2 |
Issue number | 6095 |
Pages (from-to) | 1117-9 |
Number of pages | 2 |
ISSN | 0007-1447 |
Publication status | Published - 1977 |
Bibliographical note
Keywords: Amniocentesis; Chromosome Aberrations; Chromosome Disorders; Evaluation Studies as Topic; Female; Fetal Diseases; Humans; Pregnancy; Prenatal Diagnosis; Risk
ID: 4853578