Selected testosterone-related diseases in women who have given birth to a child with infantile autism
Research output: Contribution to journal › Journal article › Research › peer-review
AIM: The objective of the current study was to compare the prevalence of three testosterone-related cancer diseases in the mothers of 111 individuals diagnosed as children with infantile autism (IA) with a matched comparison group of mothers of 330 children from the general population. METHOD: All mothers were screened through the nationwide Danish National Hospital Register. We inquired about breast-, uterine-, and ovarian cancer diseases during an observation period of 27 years. RESULTS: At follow up a similar proportion of case and control mothers had a diagnosis of any cancer disease: 6.3% vs 8.5%. In addition, no single cancer disease was significantly more frequent among mothers of children with IA. CONCLUSION: Our study provides no support for an (eventually androgen-mediated) increased rate of cancer in mothers of persons with IA.
Original language | English |
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Journal | Psychiatry and Clinical Neurosciences |
Volume | 63 |
Issue number | 4 |
Pages (from-to) | 586-90 |
Number of pages | 4 |
ISSN | 1323-1316 |
DOIs | |
Publication status | Published - 2009 |
Bibliographical note
Keywords: Adult; Age Factors; Aged; Aged, 80 and over; Autistic Disorder; Breast Neoplasms; Child; Child of Impaired Parents; Child, Preschool; Denmark; Female; Follow-Up Studies; Genital Neoplasms, Female; Humans; Male; Middle Aged; Mothers; Ovarian Neoplasms; Pregnancy; Prenatal Exposure Delayed Effects; Prevalence; Sex Distribution; Testosterone; Uterine Neoplasms
ID: 21406369