Prevention of postoperative ileus.

Research output: Contribution to journal › Review › Research

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Prevention of postoperative ileus. / Holte, Kathrine; Kehlet, H.

In: Minerva Anestesiologica, Vol. 68, No. 4, 2002, p. 152-156.

Research output: Contribution to journal › Review › Research

Harvard

Holte, K & Kehlet, H 2002, 'Prevention of postoperative ileus.', Minerva Anestesiologica, vol. 68, no. 4, pp. 152-156. <http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=12024073&query_hl=62>

APA

Holte, K., & Kehlet, H. (2002). Prevention of postoperative ileus. Minerva Anestesiologica, 68(4), 152-156. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=12024073&query_hl=62

Vancouver

Holte K, Kehlet H. Prevention of postoperative ileus. Minerva Anestesiologica. 2002;68(4):152-156.

Author

Holte, Kathrine ; Kehlet, H. / Prevention of postoperative ileus. In: Minerva Anestesiologica. 2002 ; Vol. 68, No. 4. pp. 152-156.

Bibtex

@article{9f75e4950d424341940cc10dfcfd8162,
title = "Prevention of postoperative ileus.",
abstract = "Postoperative ileus (PI) is a major contributor to postoperative morbidity and prolonged convalescence after major surgical procedures. The pathophysiology of PI is multifactorial, including activation of the stress response to surgery, with inhibitory sympathetic visceral reflexes and inflammatory mediators. We update evidence on the advances in the prevention and treatment on PI. As single interventions, continuous thoracic epidural analgesia with local anesthetics and minimally invasive surgery are the most efficient interventions in the reduction of PI. The effects of pharmacological agents have generally been disappointing with the exception of cisapride and the introduction of the new selective peripherally acting m-opioid antagonists. Presently, introduction of a multi-modal rehabilitation programme (including continuous epidural analgesia with local anesthetics, early oral feeding and enforced mobilization) is the most effective technique to reduce PI in abdominal procedures.",
author = "Kathrine Holte and H Kehlet",
year = "2002",
language = "English",
volume = "68",
pages = "152--156",
journal = "Minerva Anestesiologica",
issn = "0375-9393",
publisher = "EdizioniMinerva Medica",
number = "4",

}

RIS

TY - JOUR

T1 - Prevention of postoperative ileus.

AU - Holte, Kathrine

AU - Kehlet, H

PY - 2002

Y1 - 2002

N2 - Postoperative ileus (PI) is a major contributor to postoperative morbidity and prolonged convalescence after major surgical procedures. The pathophysiology of PI is multifactorial, including activation of the stress response to surgery, with inhibitory sympathetic visceral reflexes and inflammatory mediators. We update evidence on the advances in the prevention and treatment on PI. As single interventions, continuous thoracic epidural analgesia with local anesthetics and minimally invasive surgery are the most efficient interventions in the reduction of PI. The effects of pharmacological agents have generally been disappointing with the exception of cisapride and the introduction of the new selective peripherally acting m-opioid antagonists. Presently, introduction of a multi-modal rehabilitation programme (including continuous epidural analgesia with local anesthetics, early oral feeding and enforced mobilization) is the most effective technique to reduce PI in abdominal procedures.

AB - Postoperative ileus (PI) is a major contributor to postoperative morbidity and prolonged convalescence after major surgical procedures. The pathophysiology of PI is multifactorial, including activation of the stress response to surgery, with inhibitory sympathetic visceral reflexes and inflammatory mediators. We update evidence on the advances in the prevention and treatment on PI. As single interventions, continuous thoracic epidural analgesia with local anesthetics and minimally invasive surgery are the most efficient interventions in the reduction of PI. The effects of pharmacological agents have generally been disappointing with the exception of cisapride and the introduction of the new selective peripherally acting m-opioid antagonists. Presently, introduction of a multi-modal rehabilitation programme (including continuous epidural analgesia with local anesthetics, early oral feeding and enforced mobilization) is the most effective technique to reduce PI in abdominal procedures.

M3 - Review

VL - 68

SP - 152

EP - 156

JO - Minerva Anestesiologica

JF - Minerva Anestesiologica

SN - 0375-9393

IS - 4

ER -

ID: 34175190