Physical Model for Investigating Intracranial Pressure with Clinical Pressure Sensors and Diagnostic Ultrasound: Preliminary Results

Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

  • Rikke von Barm
  • Isabel Martinez Tejada
  • Juhler, Marianne
  • Morten Andresen
  • Jens E. Wilhjelm

Introduction: Intracranial pressure (ICP) is a commonly collected neurocritical parameter, but accurate signal modelling remains challenging. The goal of this project was to mimic clinical ICP waveforms using a physical model. Materials and Methods: A physical head model was developed. The skull was segmented from a head computed tomography (CT) scan, remodelled, 3D-printed, and filled with a brain tissue mimicking material and a pressure generator. Pressure measurements and tissue displacement around an attached pressure sensor were explored. Results: Analysis of the measured pressure demonstrated that the waveform did not perfectly resemble that of the clinical ICP. Through iterative improvements and using a revised second pressure generator, subpeaks could be seen in the waveform. A speckle image recorded using ultrasound during pressure application enabled visualization of tissue displacement around the pressure sensor. Comparison with measured ICP signals revealed that minuscule patterns were not distinct in the displacement images. Discussion: We present the first steps towards mimicking clinical ICP using a physical head phantom model. The physical model enabled pressure tests and visualization of tissue displacement and will be foundational for further improvements.

Original languageEnglish
Title of host publicationActa Neurochirurgica Supplementum
EditorsBart Depreitere, Geert Meyfroidt, Fabian Güiza
Number of pages4
Volume131
PublisherSpringer Science and Business Media Deutschland GmbH
Publication date2021
Pages263-266
ChapterVIII
ISBN (Print)978-3-030-59435-0
ISBN (Electronic)978-3-030-59436-7
DOIs
Publication statusPublished - 2021
SeriesActa Neurochirurgica, Supplementum
Volume131
ISSN0065-1419

Bibliographical note

Funding Information:
The financial support for participating in this conference from the Otto Moensteds Foundation is greatly appreciated. Furthermore, a thanks go to BK Medical for the use of their transducer and transducer covers as well as to the Center for Fast Ultrasound for letting us use their ultrasound scanner bk5000 (BK Medical). Lastly, access to the software DataLogger provided by Raumedic Company is appreciated.

Publisher Copyright:
© 2021, Springer Nature Switzerland AG.

    Research areas

  • Intracranial pressure, Simple physical head phantom model, Tissue displacement using ultrasound

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