Influence of a microemulsion vehicle on cutaneous bioequivalence of a lipophilic model drug assessed by microdialysis and pharmacodynamics
Research output: Contribution to journal › Journal article › Research › peer-review
The aim of the study was to investigate the cutaneous bioequivalence of a lipophilic model drug (lidocaine) applied in a novel topical microemulsion vehicle, compared to a conventional oil-in-water (O/W) emulsion, assessed by a pharmacokinetics microdialysis model and a pharmacodynamic method.
| Original language | English |
|---|---|
| Journal | Pharmaceutical Research |
| Volume | 18 |
| Issue number | 5 |
| Pages (from-to) | 593-9 |
| Number of pages | 7 |
| ISSN | 0724-8741 |
| Publication status | Published - May 2001 |
- Administration, Topical, Adult, Algorithms, Anesthetics, Local, Chemistry, Physical, Chromatography, High Pressure Liquid, Emulsions, Humans, Lidocaine, Male, Microdialysis, Pain Measurement, Pharmaceutical Vehicles, Physicochemical Phenomena, Skin Absorption, Therapeutic Equivalency
Research areas
ID: 100995586