Cortical spreading depression in migraine

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Cortical spreading depression in migraine. / Lauritzen, M.

In: Cephalalgia, Vol. 21, No. 7, 01.12.2001, p. 757-760.

Research output: Contribution to journalReviewResearchpeer-review

Harvard

Lauritzen, M 2001, 'Cortical spreading depression in migraine', Cephalalgia, vol. 21, no. 7, pp. 757-760. https://doi.org/10.1046/j.1468-2982.2001.00244.x

APA

Lauritzen, M. (2001). Cortical spreading depression in migraine. Cephalalgia, 21(7), 757-760. https://doi.org/10.1046/j.1468-2982.2001.00244.x

Vancouver

Lauritzen M. Cortical spreading depression in migraine. Cephalalgia. 2001 Dec 1;21(7):757-760. https://doi.org/10.1046/j.1468-2982.2001.00244.x

Author

Lauritzen, M. / Cortical spreading depression in migraine. In: Cephalalgia. 2001 ; Vol. 21, No. 7. pp. 757-760.

Bibtex

@article{0bf2e202835a4d319615381987fc08af,
title = "Cortical spreading depression in migraine",
abstract = "Cortical spreading depression (CSD) is associated with a dramatic failure of brain ion homeostasis as well as efflux of excitatory amino acids from nerve cells and increased energy metabolism. There is strong clinical and experimental evidence to suggest that CSD is involved in the mechanism of migraine. This paper will, based on the experience related to the detection of CSD in humans, discuss pitfalls and possible strategies for detection of CSD in man. Development of reliable methods for detection of CSD in humans will determine the extent to which the large body of experimental findings from animal studies of CSD can be applied to the investigation and treatment of human brain disease. The paper is based on the experience that has been gained from two decades of studies of CSD in relation to clinical neurological diseases.",
keywords = "Cerebral blood flow, Cortical spreading, Depression",
author = "M. Lauritzen",
year = "2001",
month = dec,
day = "1",
doi = "10.1046/j.1468-2982.2001.00244.x",
language = "English",
volume = "21",
pages = "757--760",
journal = "Cephalalgia",
issn = "0800-1952",
publisher = "SAGE Publications",
number = "7",

}

RIS

TY - JOUR

T1 - Cortical spreading depression in migraine

AU - Lauritzen, M.

PY - 2001/12/1

Y1 - 2001/12/1

N2 - Cortical spreading depression (CSD) is associated with a dramatic failure of brain ion homeostasis as well as efflux of excitatory amino acids from nerve cells and increased energy metabolism. There is strong clinical and experimental evidence to suggest that CSD is involved in the mechanism of migraine. This paper will, based on the experience related to the detection of CSD in humans, discuss pitfalls and possible strategies for detection of CSD in man. Development of reliable methods for detection of CSD in humans will determine the extent to which the large body of experimental findings from animal studies of CSD can be applied to the investigation and treatment of human brain disease. The paper is based on the experience that has been gained from two decades of studies of CSD in relation to clinical neurological diseases.

AB - Cortical spreading depression (CSD) is associated with a dramatic failure of brain ion homeostasis as well as efflux of excitatory amino acids from nerve cells and increased energy metabolism. There is strong clinical and experimental evidence to suggest that CSD is involved in the mechanism of migraine. This paper will, based on the experience related to the detection of CSD in humans, discuss pitfalls and possible strategies for detection of CSD in man. Development of reliable methods for detection of CSD in humans will determine the extent to which the large body of experimental findings from animal studies of CSD can be applied to the investigation and treatment of human brain disease. The paper is based on the experience that has been gained from two decades of studies of CSD in relation to clinical neurological diseases.

KW - Cerebral blood flow

KW - Cortical spreading

KW - Depression

UR - http://www.scopus.com/inward/record.url?scp=0035741150&partnerID=8YFLogxK

U2 - 10.1046/j.1468-2982.2001.00244.x

DO - 10.1046/j.1468-2982.2001.00244.x

M3 - Review

C2 - 11595007

AN - SCOPUS:0035741150

VL - 21

SP - 757

EP - 760

JO - Cephalalgia

JF - Cephalalgia

SN - 0800-1952

IS - 7

ER -

ID: 200874638