Cold Water and Pauses in Illumination Reduces Pain During Photodynamic Therapy: A Randomized Clinical Study
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Cold Water and Pauses in Illumination Reduces Pain During Photodynamic Therapy: A Randomized Clinical Study. / Wiegell, S.R.; Haedersdal, M.; Wulf, H.C.
In: Acta Dermato Venereologica, Vol. 89, No. 2, 2009, p. 145-149.Research output: Contribution to journal › Journal article › Research › peer-review
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TY - JOUR
T1 - Cold Water and Pauses in Illumination Reduces Pain During Photodynamic Therapy: A Randomized Clinical Study
AU - Wiegell, S.R.
AU - Haedersdal, M.
AU - Wulf, H.C.
N1 - Times Cited: 1ArticleEnglishWiegell, S. RBispebjerg Hosp, Dept Dermatol D92, Bispebjerg Bakke 23, DK-2400 Copenhagen, NV, DenmarkCited References Count: 10424TWACTA DERMATO-VENEREOLOGICATRADGARDSGATAN 14, UPPSALA, SE-753 09, SWEDENUPPSALA
PY - 2009
Y1 - 2009
N2 - Pain is the main acute adverse event during photodynamic therapy of skin lesions. The objective of this randomized study was to evaluate the pain-relieving effect of pauses and cooling during illumination. Twenty-four patients with actinic keratoses were treated with photodynamic therapy in two symmetrical areas and cooled with either cold-water-spray or cold-water-pack (Coo]Pack). Treatment areas were cooled during either the first or second period of illumination, which were separated by a 3-min pause in illumination. Pain intensity was scored from 0 to 10. Water-spray reduced the mean pain score by 1.2 points (p=0.030) and CoolPack by 1.3 points (p=0.007) during the first half of the illumination. Pain intensity decreased during the pause by 3.7 points in water-spray patients (p<0.0001) and 3.0 points in CoolPack patients (p<0.0001). In conclusion, cooling resulted in a minor reduction in pain intensity, while adding the intermediate pause in illumination reduced the pain considerably. Use of pauses and cooling during illumination is an easy and inexpensive way to make photodynamic therapy more tolerable for the patient Udgivelsesdato: 2009
AB - Pain is the main acute adverse event during photodynamic therapy of skin lesions. The objective of this randomized study was to evaluate the pain-relieving effect of pauses and cooling during illumination. Twenty-four patients with actinic keratoses were treated with photodynamic therapy in two symmetrical areas and cooled with either cold-water-spray or cold-water-pack (Coo]Pack). Treatment areas were cooled during either the first or second period of illumination, which were separated by a 3-min pause in illumination. Pain intensity was scored from 0 to 10. Water-spray reduced the mean pain score by 1.2 points (p=0.030) and CoolPack by 1.3 points (p=0.007) during the first half of the illumination. Pain intensity decreased during the pause by 3.7 points in water-spray patients (p<0.0001) and 3.0 points in CoolPack patients (p<0.0001). In conclusion, cooling resulted in a minor reduction in pain intensity, while adding the intermediate pause in illumination reduced the pain considerably. Use of pauses and cooling during illumination is an easy and inexpensive way to make photodynamic therapy more tolerable for the patient Udgivelsesdato: 2009
M3 - Journal article
VL - 89
SP - 145
EP - 149
JO - Acta Dermato-Venereologica
JF - Acta Dermato-Venereologica
SN - 0001-5555
IS - 2
ER -
ID: 20683449