Analogues of [3H] chloramphenicol for photoaffinity labeling
Research output: Contribution to journal › Journal article › Research › peer-review
The synthesis of [3H]chloramphenicol and its erythro-diastereoisomer with specific activities of 1.25 Ci/mmol, and the further transformation of the [3H]chloramphenicol to a series of azido and diazo-substituted derivatives are described. The antibiotic activity of the compounds was considered insufficient for their use as photoaffinity labels.
| Original language | English |
|---|---|
| Journal | Hoppe-Seyler's Zeitschrift fur Physiologische Chemie |
| Volume | 360 |
| Issue number | 6 |
| Pages (from-to) | 721-4 |
| Number of pages | 4 |
| ISSN | 0018-4888 |
| DOIs | |
| Publication status | Published - Jun 1979 |
- Affinity Labels, Chemical Phenomena, Chemistry, Chloramphenicol/analogs & derivatives, Escherichia coli/drug effects, Isotope Labeling/methods, Ribosomes/drug effects, Tritium
Research areas
ID: 203631991