Uncoupling of cerebral blood flow and metabolism after single episode of cortical spreading depression in the rat brain
Research output: Contribution to journal › Journal article › Research › peer-review
The present study was undertaken to evaluate whether the persistent hypoperfusion following cortical spreading depression (CSD) in rat brain was accompanied by alterations of regional cortical glucose consumption (rCGU). rCGU was measured using 2-deoxy-[14C]glucose and autoradiography at 15-60 min after single CSD episodes. rCGU did not differ in cortical regions invaded by CSD as compared to the contralateral side and to sham-treated rats. The results suggested impairment of the metabolism-flow couple after CSD.
| Original language | English |
|---|---|
| Journal | Brain Research |
| Volume | 370 |
| Issue number | 2 |
| Pages (from-to) | 405-408 |
| Number of pages | 4 |
| ISSN | 0006-8993 |
| DOIs | |
| Publication status | Published - 9 Apr 1986 |
- cerebral glucose consumption, spreading depression
Research areas
ID: 201457482