TY - JOUR

T1 - Longevity of posterior composite restorations: A systematic review and meta-analysis

AU - Opdam, Niek

AU - van de Sande, Francoise

AU - Bronkhorst, Ewald

AU - Bottenberg, Peter

AU - Cenci, Maximiliano

AU - Gaengler, Peter

AU - Pallesen, Ulla

AU - Lindberg, Anders

AU - Huysmans, Marie-Charlotte

AU - van Dijken, Jan WV

PY - 2014

Y1 - 2014

N2 - The aim of this meta-analysis, based on individual participant data ofseveral studies, was to investigate the influence of patient, materials andtooth related variables on the survival of posterior resin compositerestorations.Methods: Following PRISMA guidelines a search was conducted resulting in12 longitudinal studies of direct posterior resin composite restorations withat least 5 years follow-up. Original datasets were still available, includingplacement/failure/censoring of restorations, restored surfaces, materialsused, reasons for clinical failure, and caries-risk status. A databaseincluding all restorations was constructed and a Multivariate Cox’sregression method was used to analyze variables of interest [patient (age;gender; caries-risk-status), jaw (upper; lower), number of restoredsurfaces, resin composite and adhesive materials and use of glass-ionomercement as base/liner (present or absent)] The Hazard Ratios withrespective 95% confidence intervals were determined and annual failurerates were calculated for subgroups.Results: 2816 restorations (2585 Class II and 231 class I restorations)were included in the analysis, of which 569 failed during the observationperiod. Main reasons for failure were caries and fracture. The regressionanalyses showed a significantly higher risk of failure for restorations in highcaries risk individuals and with a higher number of restored surfaces.

AB - The aim of this meta-analysis, based on individual participant data ofseveral studies, was to investigate the influence of patient, materials andtooth related variables on the survival of posterior resin compositerestorations.Methods: Following PRISMA guidelines a search was conducted resulting in12 longitudinal studies of direct posterior resin composite restorations withat least 5 years follow-up. Original datasets were still available, includingplacement/failure/censoring of restorations, restored surfaces, materialsused, reasons for clinical failure, and caries-risk status. A databaseincluding all restorations was constructed and a Multivariate Cox’sregression method was used to analyze variables of interest [patient (age;gender; caries-risk-status), jaw (upper; lower), number of restoredsurfaces, resin composite and adhesive materials and use of glass-ionomercement as base/liner (present or absent)] The Hazard Ratios withrespective 95% confidence intervals were determined and annual failurerates were calculated for subgroups.Results: 2816 restorations (2585 Class II and 231 class I restorations)were included in the analysis, of which 569 failed during the observationperiod. Main reasons for failure were caries and fracture. The regressionanalyses showed a significantly higher risk of failure for restorations in highcaries risk individuals and with a higher number of restored surfaces.

KW - Faculty of Health and Medical Sciences

KW - Composite materials, Restorative materials, Risk factor(s), Operative

U2 - 10.1177/0022034514544217

DO - 10.1177/0022034514544217

M3 - Journal article

C2 - 25048250

VL - 93

SP - 943

EP - 949

JO - Journal of Dental Research

JF - Journal of Dental Research

SN - 0022-0345

IS - 10

ER -