Humoral and cell-mediated immune responses in DNA immunized mink challenged with wild-type canine distemper virus

Research output: Contribution to journal › Journal article › Research › peer-review

Standard

Humoral and cell-mediated immune responses in DNA immunized mink challenged with wild-type canine distemper virus. / Nielsen, Line; Søgaard, Mette; Karlskov-Mortensen, Peter; Jensen, Trine Hammer; Jensen, Tove Johanne Dannemann; Aasted, Bent; Blixenkrone-Møller, Merete.

In: Vaccine, Vol. 27, No. 35, 2009, p. 4791-4797.

Research output: Contribution to journal › Journal article › Research › peer-review

Harvard

Nielsen, L, Søgaard, M, Karlskov-Mortensen, P, Jensen, TH, Jensen, TJD, Aasted, B & Blixenkrone-Møller, M 2009, 'Humoral and cell-mediated immune responses in DNA immunized mink challenged with wild-type canine distemper virus', Vaccine, vol. 27, no. 35, pp. 4791-4797. https://doi.org/10.1016/j.vaccine.2009.05.090

APA

Nielsen, L., Søgaard, M., Karlskov-Mortensen, P., Jensen, T. H., Jensen, T. J. D., Aasted, B., & Blixenkrone-Møller, M. (2009). Humoral and cell-mediated immune responses in DNA immunized mink challenged with wild-type canine distemper virus. Vaccine, 27(35), 4791-4797. https://doi.org/10.1016/j.vaccine.2009.05.090

Vancouver

Nielsen L, Søgaard M, Karlskov-Mortensen P, Jensen TH, Jensen TJD, Aasted B et al. Humoral and cell-mediated immune responses in DNA immunized mink challenged with wild-type canine distemper virus. Vaccine. 2009;27(35):4791-4797. https://doi.org/10.1016/j.vaccine.2009.05.090

Author

Nielsen, Line ; Søgaard, Mette ; Karlskov-Mortensen, Peter ; Jensen, Trine Hammer ; Jensen, Tove Johanne Dannemann ; Aasted, Bent ; Blixenkrone-Møller, Merete. / Humoral and cell-mediated immune responses in DNA immunized mink challenged with wild-type canine distemper virus. In: Vaccine. 2009 ; Vol. 27, No. 35. pp. 4791-4797.

Bibtex

@article{1ea826507c3911de8bc9000ea68e967b,
title = "Humoral and cell-mediated immune responses in DNA immunized mink challenged with wild-type canine distemper virus",
abstract = "The aim of the study was to investigate the different phases of the immune response after DNA immunization with the hemagglutinin and nucleoprotein genes from canine distemper virus (CDV). Although attenuated live CDV vaccines have effectively reduced the incidence of disease, canine distemper is still a problem worldwide. The broad host range of CDV creates a constant viral reservoir among wildlife animals. Our results demonstrated early humoral and cell-mediated immune responses (IFN-gamma) in DNA vaccinated mink compared to mock-vaccinated mink after challenge with a Danish wild-type CDV. The DNA vaccine-induced immunity protected the natural host against disease development.",
keywords = "Former Faculty of Life Sciences",
author = "Line Nielsen and Mette S{\o}gaard and Peter Karlskov-Mortensen and Jensen, {Trine Hammer} and Jensen, {Tove Johanne Dannemann} and Bent Aasted and Merete Blixenkrone-M{\o}ller",
year = "2009",
doi = "10.1016/j.vaccine.2009.05.090",
language = "English",
volume = "27",
pages = "4791--4797",
journal = "Vaccine",
issn = "0264-410X",
publisher = "Elsevier",
number = "35",

}

RIS

TY - JOUR

T1 - Humoral and cell-mediated immune responses in DNA immunized mink challenged with wild-type canine distemper virus

AU - Nielsen, Line

AU - Søgaard, Mette

AU - Karlskov-Mortensen, Peter

AU - Jensen, Trine Hammer

AU - Jensen, Tove Johanne Dannemann

AU - Aasted, Bent

AU - Blixenkrone-Møller, Merete

PY - 2009

Y1 - 2009

N2 - The aim of the study was to investigate the different phases of the immune response after DNA immunization with the hemagglutinin and nucleoprotein genes from canine distemper virus (CDV). Although attenuated live CDV vaccines have effectively reduced the incidence of disease, canine distemper is still a problem worldwide. The broad host range of CDV creates a constant viral reservoir among wildlife animals. Our results demonstrated early humoral and cell-mediated immune responses (IFN-gamma) in DNA vaccinated mink compared to mock-vaccinated mink after challenge with a Danish wild-type CDV. The DNA vaccine-induced immunity protected the natural host against disease development.

AB - The aim of the study was to investigate the different phases of the immune response after DNA immunization with the hemagglutinin and nucleoprotein genes from canine distemper virus (CDV). Although attenuated live CDV vaccines have effectively reduced the incidence of disease, canine distemper is still a problem worldwide. The broad host range of CDV creates a constant viral reservoir among wildlife animals. Our results demonstrated early humoral and cell-mediated immune responses (IFN-gamma) in DNA vaccinated mink compared to mock-vaccinated mink after challenge with a Danish wild-type CDV. The DNA vaccine-induced immunity protected the natural host against disease development.

KW - Former Faculty of Life Sciences

U2 - 10.1016/j.vaccine.2009.05.090

DO - 10.1016/j.vaccine.2009.05.090

M3 - Journal article

C2 - 19539579

VL - 27

SP - 4791

EP - 4797

JO - Vaccine

JF - Vaccine

SN - 0264-410X

IS - 35

ER -

ID: 13413254