Hebbian plasticity in vivo: relevance and induction.

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Hebbian plasticity in vivo: relevance and induction. / Andersen, Niels; Krauth, N; Nabavi, S.

In: Current Opinion in Neurobiology, Vol. 45, 2017, p. 188-192.

Research output: Contribution to journal › Journal article › Research › peer-review

Harvard

Andersen, N, Krauth, N & Nabavi, S 2017, 'Hebbian plasticity in vivo: relevance and induction.', Current Opinion in Neurobiology, vol. 45, pp. 188-192. https://doi.org/10.1016/j.conb.2017.06.001

APA

Andersen, N., Krauth, N., & Nabavi, S. (2017). Hebbian plasticity in vivo: relevance and induction. Current Opinion in Neurobiology, 45, 188-192. https://doi.org/10.1016/j.conb.2017.06.001

Vancouver

Andersen N, Krauth N, Nabavi S. Hebbian plasticity in vivo: relevance and induction. Current Opinion in Neurobiology. 2017;45:188-192. https://doi.org/10.1016/j.conb.2017.06.001

Author

Andersen, Niels ; Krauth, N ; Nabavi, S. / Hebbian plasticity in vivo: relevance and induction. In: Current Opinion in Neurobiology. 2017 ; Vol. 45. pp. 188-192.

Bibtex

@article{c00273e6b9d7418680c8efc6834a9a8f,
title = "Hebbian plasticity in vivo: relevance and induction.",
abstract = "Hebbian plasticity, as represented by long-term potentiation (LTP) and long-term depression (LTD) of synapses, has been the most influential hypothesis to account for encoding of memories. The evidence for the physiological relevance of LTP is indisputable. However, until recently the ways by which LTP physiologically is induced in its natural environment, the brain, was less clear. Nonetheless, current evidence points to neuromodulators as an indispensable element. The case for LTD in vivo is less certain. Even its relevance has been a matter of speculation and doubts. However, emerging evidence for a physiological role for LTD is promising, as the phenomenon has been observed at different brain regions. More needs to be done before LTD can claim an equal status alongside LTP.",
author = "Niels Andersen and N Krauth and S Nabavi",
year = "2017",
doi = "10.1016/j.conb.2017.06.001",
language = "English",
volume = "45",
pages = "188--192",
journal = "Current Opinion in Neurobiology",
issn = "0959-4388",
publisher = "Elsevier Ltd. * Current Opinion Journals",

}

RIS

TY - JOUR

T1 - Hebbian plasticity in vivo: relevance and induction.

AU - Andersen, Niels

AU - Krauth, N

AU - Nabavi, S

PY - 2017

Y1 - 2017

N2 - Hebbian plasticity, as represented by long-term potentiation (LTP) and long-term depression (LTD) of synapses, has been the most influential hypothesis to account for encoding of memories. The evidence for the physiological relevance of LTP is indisputable. However, until recently the ways by which LTP physiologically is induced in its natural environment, the brain, was less clear. Nonetheless, current evidence points to neuromodulators as an indispensable element. The case for LTD in vivo is less certain. Even its relevance has been a matter of speculation and doubts. However, emerging evidence for a physiological role for LTD is promising, as the phenomenon has been observed at different brain regions. More needs to be done before LTD can claim an equal status alongside LTP.

AB - Hebbian plasticity, as represented by long-term potentiation (LTP) and long-term depression (LTD) of synapses, has been the most influential hypothesis to account for encoding of memories. The evidence for the physiological relevance of LTP is indisputable. However, until recently the ways by which LTP physiologically is induced in its natural environment, the brain, was less clear. Nonetheless, current evidence points to neuromodulators as an indispensable element. The case for LTD in vivo is less certain. Even its relevance has been a matter of speculation and doubts. However, emerging evidence for a physiological role for LTD is promising, as the phenomenon has been observed at different brain regions. More needs to be done before LTD can claim an equal status alongside LTP.

UR - http://europepmc.org/abstract/med/28683352

U2 - 10.1016/j.conb.2017.06.001

DO - 10.1016/j.conb.2017.06.001

M3 - Journal article

C2 - 28683352

VL - 45

SP - 188

EP - 192

JO - Current Opinion in Neurobiology

JF - Current Opinion in Neurobiology

SN - 0959-4388

ER -

ID: 247986958