Estimating the costs of implementing the rotavirus vaccine in the national immunisation programme: the case of Malawi.

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Estimating the costs of implementing the rotavirus vaccine in the national immunisation programme: the case of Malawi. / Madsen, Lizell Bustamante; Ustrup, Marte; Hansen, Karsten S.; Nyasulu, Peter S. ; Bygbjerg, Ib Christian; Konradsen, Flemming.

In: Tropical Medicine & International Health, Vol. 19, No. 2, 02.2014, p. 177-185.

Research output: Contribution to journalJournal articleResearchpeer-review

Harvard

Madsen, LB, Ustrup, M, Hansen, KS, Nyasulu, PS, Bygbjerg, IC & Konradsen, F 2014, 'Estimating the costs of implementing the rotavirus vaccine in the national immunisation programme: the case of Malawi.', Tropical Medicine & International Health, vol. 19, no. 2, pp. 177-185. https://doi.org/10.1111/tmi.12233

APA

Madsen, L. B., Ustrup, M., Hansen, K. S., Nyasulu, P. S., Bygbjerg, I. C., & Konradsen, F. (2014). Estimating the costs of implementing the rotavirus vaccine in the national immunisation programme: the case of Malawi. Tropical Medicine & International Health, 19(2), 177-185. https://doi.org/10.1111/tmi.12233

Vancouver

Madsen LB, Ustrup M, Hansen KS, Nyasulu PS, Bygbjerg IC, Konradsen F. Estimating the costs of implementing the rotavirus vaccine in the national immunisation programme: the case of Malawi. Tropical Medicine & International Health. 2014 Feb;19(2):177-185. https://doi.org/10.1111/tmi.12233

Author

Madsen, Lizell Bustamante ; Ustrup, Marte ; Hansen, Karsten S. ; Nyasulu, Peter S. ; Bygbjerg, Ib Christian ; Konradsen, Flemming. / Estimating the costs of implementing the rotavirus vaccine in the national immunisation programme: the case of Malawi. In: Tropical Medicine & International Health. 2014 ; Vol. 19, No. 2. pp. 177-185.

Bibtex

@article{eee4f385b39e4be6bb97521084d88bf9,
title = "Estimating the costs of implementing the rotavirus vaccine in the national immunisation programme: the case of Malawi.",
abstract = "OBJECTIVES: Worldwide, rotavirus infections cause approximately 453,000 child deaths annually. Two licensed vaccines could be life- and cost-saving in low-income countries where the disease burden is highest. The aim of our study was to estimate the total cost of implementing the rotavirus vaccine in the national immunisation programme of a low-income country. Furthermore, the aim was to examine the relative contribution of different components to the total cost.METHODS: Following the World Health Organization guidelines, we estimated the resource use and costs associated with rotavirus vaccine implementation, using Malawi as a case. The cost analysis was undertaken from a governmental perspective. All costs were calculated for a 5-years period (2012-2016) and discounted at 5{\%}. The value of key input parameters was varied in a sensitivity analysis.RESULTS: The total cost of rotavirus vaccine implementation in Malawi amounted to US$ 18.5 million over a 5-years period. This translated into US$ 5.8 per child in the birth cohort. With GAVI Alliance financial support, the total cost was reduced to US$ 1.4 per child in the birth cohort. Approximately 83{\%} of the total cost was attributed to vaccine purchase, while 17{\%} was attributed to system costs, with personnel, transportation and cold chain as the main cost components.CONCLUSION: The total cost of rotavirus vaccine implementation in Malawi is high compared with the governmental health budget of US$ 26 per capita per year. This highlights the need for new financing opportunities for low-income countries to facilitate vaccine implementation and ensure sustainable financing.",
keywords = "Faculty of Health and Medical Sciences, costs, cost analysis, developing countries, immunisation programmes, Malawi, rotavirus",
author = "Madsen, {Lizell Bustamante} and Marte Ustrup and Hansen, {Karsten S.} and Nyasulu, {Peter S.} and Bygbjerg, {Ib Christian} and Flemming Konradsen",
year = "2014",
month = "2",
doi = "10.1111/tmi.12233",
language = "English",
volume = "19",
pages = "177--185",
journal = "Tropical Medicine & International Health",
issn = "1360-2276",
publisher = "Wiley-Blackwell",
number = "2",

}

RIS

TY - JOUR

T1 - Estimating the costs of implementing the rotavirus vaccine in the national immunisation programme: the case of Malawi.

AU - Madsen, Lizell Bustamante

AU - Ustrup, Marte

AU - Hansen, Karsten S.

AU - Nyasulu, Peter S.

AU - Bygbjerg, Ib Christian

AU - Konradsen, Flemming

PY - 2014/2

Y1 - 2014/2

N2 - OBJECTIVES: Worldwide, rotavirus infections cause approximately 453,000 child deaths annually. Two licensed vaccines could be life- and cost-saving in low-income countries where the disease burden is highest. The aim of our study was to estimate the total cost of implementing the rotavirus vaccine in the national immunisation programme of a low-income country. Furthermore, the aim was to examine the relative contribution of different components to the total cost.METHODS: Following the World Health Organization guidelines, we estimated the resource use and costs associated with rotavirus vaccine implementation, using Malawi as a case. The cost analysis was undertaken from a governmental perspective. All costs were calculated for a 5-years period (2012-2016) and discounted at 5%. The value of key input parameters was varied in a sensitivity analysis.RESULTS: The total cost of rotavirus vaccine implementation in Malawi amounted to US$ 18.5 million over a 5-years period. This translated into US$ 5.8 per child in the birth cohort. With GAVI Alliance financial support, the total cost was reduced to US$ 1.4 per child in the birth cohort. Approximately 83% of the total cost was attributed to vaccine purchase, while 17% was attributed to system costs, with personnel, transportation and cold chain as the main cost components.CONCLUSION: The total cost of rotavirus vaccine implementation in Malawi is high compared with the governmental health budget of US$ 26 per capita per year. This highlights the need for new financing opportunities for low-income countries to facilitate vaccine implementation and ensure sustainable financing.

AB - OBJECTIVES: Worldwide, rotavirus infections cause approximately 453,000 child deaths annually. Two licensed vaccines could be life- and cost-saving in low-income countries where the disease burden is highest. The aim of our study was to estimate the total cost of implementing the rotavirus vaccine in the national immunisation programme of a low-income country. Furthermore, the aim was to examine the relative contribution of different components to the total cost.METHODS: Following the World Health Organization guidelines, we estimated the resource use and costs associated with rotavirus vaccine implementation, using Malawi as a case. The cost analysis was undertaken from a governmental perspective. All costs were calculated for a 5-years period (2012-2016) and discounted at 5%. The value of key input parameters was varied in a sensitivity analysis.RESULTS: The total cost of rotavirus vaccine implementation in Malawi amounted to US$ 18.5 million over a 5-years period. This translated into US$ 5.8 per child in the birth cohort. With GAVI Alliance financial support, the total cost was reduced to US$ 1.4 per child in the birth cohort. Approximately 83% of the total cost was attributed to vaccine purchase, while 17% was attributed to system costs, with personnel, transportation and cold chain as the main cost components.CONCLUSION: The total cost of rotavirus vaccine implementation in Malawi is high compared with the governmental health budget of US$ 26 per capita per year. This highlights the need for new financing opportunities for low-income countries to facilitate vaccine implementation and ensure sustainable financing.

KW - Faculty of Health and Medical Sciences

KW - costs, cost analysis, developing countries, immunisation programmes, Malawi, rotavirus

U2 - 10.1111/tmi.12233

DO - 10.1111/tmi.12233

M3 - Journal article

C2 - 24314006

VL - 19

SP - 177

EP - 185

JO - Tropical Medicine & International Health

JF - Tropical Medicine & International Health

SN - 1360-2276

IS - 2

ER -

ID: 117625835