Inactivated Cyberlindnera jadinii yeast (previously classified as Candida utilis) produced from local lignocellulosic biomass-based sugars is an alternative protein source in diets for young pigs. The objective of this study was to evaluate the effects of diets containing C. jadinii on the nitrogen and energy metabolism and apparent total tract digestibility (ATTD) of major nutrients and energy in young pigs. Twenty-four intact boars with a mean initial body weight of 16.7 ± 4.5 kg were assigned to four diets: a conventional control diet for young pigs with soybean meal, fish meal, rapeseed meal and potato protein concentrate as major protein sources or one of three experimental diets containing 10, 20, and 40%% of crude protein (CP) from C. jadinii. The pigs were equally distributed to the dietary treatments according to initial body weight and litter, comprising a total of six replicates per diet. The experiment was carried out during three periods of 14 days. Each period comprised an energy and nitrogen balance experiment of four consecutive days including a 22 h respiration experiment by means of indirect calorimetry. Adding C. jadinii to diets did not affect the ATTD of nutrients and energy in the diets. The energy and nitrogen metabolism was not affected by partially replacing the main protein sources with C. jadinii. Collectively, the results indicate that CP from C. jadinii can replace up to 40% of dietary CP from conventional protein sources while maintaining the efficiency of nitrogen and energy metabolism in young pigs.