Adult Stromal (Skeletal, Mesenchymal) Stem Cells: Advances Towards Clinical Applications

Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review

Standard

Adult Stromal (Skeletal, Mesenchymal) Stem Cells: Advances Towards Clinical Applications. / Kermani, Abbas Jafari; Harkness, Linda; Zaher, Walid; Kassem, Moustapha Saad El-Deen.

Adult Stem Cells : Stem Cell Biology and Regenerative Medicine. ed. / Kursad Turksen. New York : Humana Press, 2014. p. 359-373.

Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review

Harvard

Kermani, AJ, Harkness, L, Zaher, W & Kassem, MSE-D 2014, Adult Stromal (Skeletal, Mesenchymal) Stem Cells: Advances Towards Clinical Applications. in K Turksen (ed.), Adult Stem Cells : Stem Cell Biology and Regenerative Medicine. Humana Press, New York, pp. 359-373. https://doi.org/10.1007/978-1-4614-9569-7_15

APA

Kermani, A. J., Harkness, L., Zaher, W., & Kassem, M. S. E-D. (2014). Adult Stromal (Skeletal, Mesenchymal) Stem Cells: Advances Towards Clinical Applications. In K. Turksen (Ed.), Adult Stem Cells : Stem Cell Biology and Regenerative Medicine (pp. 359-373). Humana Press. https://doi.org/10.1007/978-1-4614-9569-7_15

Vancouver

Kermani AJ, Harkness L, Zaher W, Kassem MSE-D. Adult Stromal (Skeletal, Mesenchymal) Stem Cells: Advances Towards Clinical Applications. In Turksen K, editor, Adult Stem Cells : Stem Cell Biology and Regenerative Medicine. New York: Humana Press. 2014. p. 359-373 https://doi.org/10.1007/978-1-4614-9569-7_15

Author

Kermani, Abbas Jafari ; Harkness, Linda ; Zaher, Walid ; Kassem, Moustapha Saad El-Deen. / Adult Stromal (Skeletal, Mesenchymal) Stem Cells: Advances Towards Clinical Applications. Adult Stem Cells : Stem Cell Biology and Regenerative Medicine. editor / Kursad Turksen. New York : Humana Press, 2014. pp. 359-373

Bibtex

@inbook{73688f1f9e514a6f849b2aec4c2bc951,
title = "Adult Stromal (Skeletal, Mesenchymal) Stem Cells: Advances Towards Clinical Applications",
abstract = "Mesenchymal Stem Cells (MSC) are non-hematopoietic adult stromal cells that reside in a perivascular niche in close association with pericytes and endothelial cells and possess self-renewal and multi-lineage differentiation capacity. The origin, unique properties, and therapeutic benefits of MSC are under intensive investigation worldwide. Several challenges with regard to the proper source of clinical-grade MSC and the efficacy of MSC-based treatment strategies need to be addressed before MSC can be routinely used in the clinic. Here, we discuss three areas that can potentially facilitate the translation of MSC into clinic: Generation of MSC-like cells from human pluripotent stem cells, strategies to enhance homing of MSC to injured tissues, and targeting of MSC in vivo.",
keywords = "Faculty of Health and Medical Sciences, Mesenchymal stem cells, MSC-like cells, Pluripotent stem cells, Homing, In vivo targeting",
author = "Kermani, {Abbas Jafari} and Linda Harkness and Walid Zaher and Kassem, {Moustapha Saad El-Deen}",
year = "2014",
doi = "10.1007/978-1-4614-9569-7_15",
language = "English",
isbn = "978-1-4614-9568-0",
pages = "359--373",
editor = "Kursad Turksen",
booktitle = "Adult Stem Cells",
publisher = "Humana Press",
address = "United States",

}

RIS

TY - CHAP

T1 - Adult Stromal (Skeletal, Mesenchymal) Stem Cells: Advances Towards Clinical Applications

AU - Kermani, Abbas Jafari

AU - Harkness, Linda

AU - Zaher, Walid

AU - Kassem, Moustapha Saad El-Deen

PY - 2014

Y1 - 2014

N2 - Mesenchymal Stem Cells (MSC) are non-hematopoietic adult stromal cells that reside in a perivascular niche in close association with pericytes and endothelial cells and possess self-renewal and multi-lineage differentiation capacity. The origin, unique properties, and therapeutic benefits of MSC are under intensive investigation worldwide. Several challenges with regard to the proper source of clinical-grade MSC and the efficacy of MSC-based treatment strategies need to be addressed before MSC can be routinely used in the clinic. Here, we discuss three areas that can potentially facilitate the translation of MSC into clinic: Generation of MSC-like cells from human pluripotent stem cells, strategies to enhance homing of MSC to injured tissues, and targeting of MSC in vivo.

AB - Mesenchymal Stem Cells (MSC) are non-hematopoietic adult stromal cells that reside in a perivascular niche in close association with pericytes and endothelial cells and possess self-renewal and multi-lineage differentiation capacity. The origin, unique properties, and therapeutic benefits of MSC are under intensive investigation worldwide. Several challenges with regard to the proper source of clinical-grade MSC and the efficacy of MSC-based treatment strategies need to be addressed before MSC can be routinely used in the clinic. Here, we discuss three areas that can potentially facilitate the translation of MSC into clinic: Generation of MSC-like cells from human pluripotent stem cells, strategies to enhance homing of MSC to injured tissues, and targeting of MSC in vivo.

KW - Faculty of Health and Medical Sciences

KW - Mesenchymal stem cells

KW - MSC-like cells

KW - Pluripotent stem cells

KW - Homing

KW - In vivo targeting

U2 - 10.1007/978-1-4614-9569-7_15

DO - 10.1007/978-1-4614-9569-7_15

M3 - Book chapter

SN - 978-1-4614-9568-0

SP - 359

EP - 373

BT - Adult Stem Cells

A2 - Turksen, Kursad

PB - Humana Press

CY - New York

ER -

ID: 138176649