The biophysics of piezo1 and piezo2 mechanosensitive channels

Research output: Contribution to journal › Journal article › Research › peer-review

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The biophysics of piezo1 and piezo2 mechanosensitive channels. / Soattin, Luca.

In: Biophysical Chemistry, Vol. 208, 2016, p. 26-33.

Research output: Contribution to journal › Journal article › Research › peer-review

Harvard

Soattin, L 2016, 'The biophysics of piezo1 and piezo2 mechanosensitive channels', Biophysical Chemistry, vol. 208, pp. 26-33. https://doi.org/10.1016/j.bpc.2015.06.013

APA

Soattin, L. (2016). The biophysics of piezo1 and piezo2 mechanosensitive channels. Biophysical Chemistry, 208, 26-33. https://doi.org/10.1016/j.bpc.2015.06.013

Vancouver

Soattin L. The biophysics of piezo1 and piezo2 mechanosensitive channels. Biophysical Chemistry. 2016;208:26-33. https://doi.org/10.1016/j.bpc.2015.06.013

Author

Soattin, Luca. / The biophysics of piezo1 and piezo2 mechanosensitive channels. In: Biophysical Chemistry. 2016 ; Vol. 208. pp. 26-33.

Bibtex

@article{19e11da6c8154f50832c560a5f4bfa98,
title = "The biophysics of piezo1 and piezo2 mechanosensitive channels",
abstract = "The ability to sense mechanical stimuli and elaborate a response to them is a fundamental process in all organisms, driving crucial mechanisms ranging from cell volume regulation up to organ development or regeneration. Nevertheless, only in few cases the underlying molecular players are known. In particular, mammals possess a large variety of mechanoreceptors, providing highly specialized functions in sensory cells, but also several housekeeping molecular systems are involved in the complex mechanism of mechanotransduction. Recently, a new class of almost ubiquitous membrane channels has been identified in mammalians, namely piezo1 and piezo2, that is thought to play a crucial role in the mechanobiology of mammals. This review focuses on recent findings on these novel channels, and highlights open biophysical questions that largely remain to be addressed. Copyright {\textcopyright} 2015 Elsevier B.V. All rights reserved.",
keywords = "Faculty of Health and Medical Sciences, piezo channels, mechanosensitivity, ION CHANNELS, MECHANOBIOLOGY",
author = "Luca Soattin",
year = "2016",
doi = "10.1016/j.bpc.2015.06.013",
language = "English",
volume = "208",
pages = "26--33",
journal = "Biophysical Chemistry",
issn = "0301-4622",
publisher = "Elsevier",

}

RIS

TY - JOUR

T1 - The biophysics of piezo1 and piezo2 mechanosensitive channels

AU - Soattin, Luca

PY - 2016

Y1 - 2016

N2 - The ability to sense mechanical stimuli and elaborate a response to them is a fundamental process in all organisms, driving crucial mechanisms ranging from cell volume regulation up to organ development or regeneration. Nevertheless, only in few cases the underlying molecular players are known. In particular, mammals possess a large variety of mechanoreceptors, providing highly specialized functions in sensory cells, but also several housekeeping molecular systems are involved in the complex mechanism of mechanotransduction. Recently, a new class of almost ubiquitous membrane channels has been identified in mammalians, namely piezo1 and piezo2, that is thought to play a crucial role in the mechanobiology of mammals. This review focuses on recent findings on these novel channels, and highlights open biophysical questions that largely remain to be addressed. Copyright © 2015 Elsevier B.V. All rights reserved.

AB - The ability to sense mechanical stimuli and elaborate a response to them is a fundamental process in all organisms, driving crucial mechanisms ranging from cell volume regulation up to organ development or regeneration. Nevertheless, only in few cases the underlying molecular players are known. In particular, mammals possess a large variety of mechanoreceptors, providing highly specialized functions in sensory cells, but also several housekeeping molecular systems are involved in the complex mechanism of mechanotransduction. Recently, a new class of almost ubiquitous membrane channels has been identified in mammalians, namely piezo1 and piezo2, that is thought to play a crucial role in the mechanobiology of mammals. This review focuses on recent findings on these novel channels, and highlights open biophysical questions that largely remain to be addressed. Copyright © 2015 Elsevier B.V. All rights reserved.

KW - Faculty of Health and Medical Sciences

KW - piezo channels

KW - mechanosensitivity

KW - ION CHANNELS

KW - MECHANOBIOLOGY

U2 - 10.1016/j.bpc.2015.06.013

DO - 10.1016/j.bpc.2015.06.013

M3 - Journal article

VL - 208

SP - 26

EP - 33

JO - Biophysical Chemistry

JF - Biophysical Chemistry

SN - 0301-4622

ER -

ID: 402959071