Research areas

  1. Published

    Phorbol Rearrangements

    Zimmermann, T., Franzyk, Henrik & Christensen, Søren Brøgger, 28 Sep 2018, In: Journal of Natural Products. 81, 9, p. 2134-2137 4 p.

    Research output: Contribution to journalJournal articlepeer-review

  2. Published

    Preparation of Enzyme-Activated Thapsigargin Prodrugs by Solid-Phase Synthesis

    Zimmermann, T., Christensen, Søren Brøgger & Franzyk, Henrik, 15 Jun 2018, In: Molecules. 23, 6, 13 p., 1463.

    Research output: Contribution to journalJournal articlepeer-review

  3. Published

    Structure/activity Relationship of Thapsigargin Inhibition on the Purified Golgi/secretory Pathway Ca2+/Mn2+-Transport ATPase (SPCA1a)

    Jialin, C., de Raeymaecker, J., Hovgaard, J. B., Smaardijk, S., Vandecaetsbeek, I., Wuytack, F., Møller, J. V., Eggermont, J., de Meyer, M., Christensen, Søren Brøgger & Vangheluwe, P., 2017, In: Journal of Biological Chemistry. 292, 17, p. 6938-6951 14 p.

    Research output: Contribution to journalJournal articlepeer-review

  4. Published

    Molecular Hybridization of Potent and Selective γ-Hydroxybutyric Acid (GHB) Ligands: Design, Synthesis, Binding Studies, and Molecular Modeling of Novel 3-Hydroxycyclopent-1-enecarboxylic Acid (HOCPCA) and trans-γ-Hydroxycrotonic Acid (T-HCA) Analogs

    Krall, J., Jensen, C. H., Bavo, F., Falk-Petersen, C. B., Haugaard, A. S., Vogensen, S. B., Tian, Y., Nittegaard-Nielsen, M., Sigurdardóttir, S. B., Kehler, J., Kongstad, Kenneth Thermann, Gloriam, David E., Clausen, Rasmus Prætorius, Harpsøe, Kasper, Wellendorph, Petrine & Frølund, Bente, 2017, In: Journal of Medicinal Chemistry. 60, 21, p. 9022-9039 18 p.

    Research output: Contribution to journalJournal articlepeer-review

  5. Published

    Lithostratigraphy, geology and geochemisttry of the volcanic rocks of the Vaigat Formation on Disko and Nuussuaq, Paleocene of West Greenland

    Pedersen, Asger Ken, Larsen, L. M. & Pedersen, G. K., 2017, Copenhagen: The Geological Survey of Denmark and Greenland. 244 p. (Geological Survey of Denmark and Greenland (GEUS) Bulletin, Vol. 39).

    Research output: Book/ReportBookpeer-review

  6. Published

    Iminolactones as Tools for Inversion of the Absolute Configuration of alpha-Amino Acids and as Inhibitors of Cancer Cell Proliferation

    Jensen, C. M., Chow, H., Chen, M., Zhai, L., Frydenvang, Karla Andrea, Liu, H., Franzyk, Henrik & Christensen, Søren Brøgger, 2016, In: European Journal of Medicinal Chemistry. 114, p. 118-133 16 p.

    Research output: Contribution to journalJournal articlepeer-review

  7. Published

    Basic characteristics and kinetics of degradation in aqueous buffer of selected diclofenac prodrugs intended for joint injection

    Mertz, Nina, Larsen, Susan Weng & Larsen, C. S., 6 Apr 2016. 1 p.

    Research output: Contribution to conferencePosterResearchpeer-review

  8. Published

    Cytochrome P450 Mediated Drug Metabolism

    Olsen, L., Jørgensen, Flemming Steen & Oostenbrink, C., 2016, New Horizons in Predictive Drug Metabolism and Pharmacokinetics. Wilson, A. G. E. (ed.). Cambridge: Royal Society of Chemistry, p. 66-78 13 p. (RSC Drug Discovery, Vol. 49).

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

  9. Published

    The potential of protein-nanomaterial interaction for advanced drug delivery

    Peng, Q. & Mu, Huiling, 23 Jan 2016, In: Journal of Controlled Release. 225, p. 121-132 12 p.

    Research output: Contribution to journalJournal articlepeer-review

  10. Published

    Kolliphor surfactants affect solubilization and bioavailability of fenofibrate. Studies of in vitro digestion and absorption in rats.

    Berthelsen, R., Holm, R., Jacobsen, Jette, Kristensen, J., Abrahamsson, B. & Mullertz, Anette , 6 Apr 2015, In: Molecular Pharmaceutics. 12, 4, p. 1062-1071 10 p.

    Research output: Contribution to journalJournal articlepeer-review

  11. Published

    Thapsigargin, origin, chemistry, structure-activity relationships and prodrug development.

    Doan, T. Q. N. & Christensen, Søren Brøgger, Oct 2015, In: Current Pharmaceutical Design. 21, 38, p. 5505-5517 13 p.

    Research output: Contribution to journalReviewpeer-review

  12. Published

    Selecting key toxins for focused development of elapid snake antivenoms and inhibitors guided by a Toxicity Score

    Laustsen, A. H. & Lohse, B., 15 Sep 2015, In: Toxicon. 104, p. 43-45 3 p.

    Research output: Contribution to journalLetterpeer-review

  13. Published

    Noter til Organisk Kemi for Biovidenskab: Organisk og bioorganisk kemi 2015

    Nielsen, J., 9 Feb 2015, 25 p.

    Research output: Other contributionEducation

  14. Published

    The PPARalpha agonist, fenofibrate decreases levels of anorectic N-acylethanolamines in the small intestine of mice

    Diep, T. A., Golbas, G. & Hansen, Harald S., 28 Jun 2014. 1 p.

    Research output: Contribution to conferenceConference abstract for conferenceResearch

  15. Published

    Investigations and design of pyridine-2-carboxylic acid thiazol-2-ylamide analogs as methionine aminopeptidase inhibitors using 3D-QSAR and molecular docking

    Hauser, Alexander Sebastian, 1 Aug 2014, In: Medicinal Chemistry Research. 23, 8, p. 3861 3875 p.

    Research output: Contribution to journalJournal articlepeer-review

  16. Published

    Development and validation of an SPE methodology combined with LC-MS/MS for the determination of four ionophores in aqueous environmental matrices

    Bak, S. A., Hansen, M., Krogh, K. A., Brandt, A., Halling-Sørensen, B. & Björklund, E., 25 Feb 2013, In: International Journal of Environmental Analytical Chemistry. 93, 14, p. 1500-1512

    Research output: Contribution to journalJournal articlepeer-review

  17. Published

    Altered anziety/depression-like behaviours in mice deficient in tetrahydrobiopterin

    Nasser, A., Birk Møller, L. & Andreasen T., Jesper, 13 Jan 2013.

    Research output: Contribution to conferenceConference abstract for conferenceResearchpeer-review

  18. Published

    Organ culture of C57BL/6 mouse arteries with LPS as an in vitro model of vascular inflammation

    Outzen, E. M., Mehryar, R., Boonen, H. C. M., Nielsen, A. S. & Sheykhzade, Majid, 28 Aug 2013. 1 p.

    Research output: Contribution to conferencePosterResearch

  19. Published

    Lactate dehydrogenase assay for assessment of polycation cytotoxicity

    Parhamifar, L., Andersen, H. & Moghimi, S. M., 2013, Nanotechnology for Nucleic Acid Delivery. Vol. 948. p. 13-22 10 p. (Methods in Molecular Biology).

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearch

  20. Exploring the solid-form landscape of pharmaceutical hydrates: transformation pathways of the sodium naproxen anhydrate-hydrate system

    Raijada, D. K., Bond, A., Larsen, F. H., Cornett, C., Qu, H. & Rantanen, J., Jan 2013, In: Pharmaceutical Research. 30, 1, p. 280-289 10 p.

    Research output: Contribution to journalJournal articlepeer-review

  21. Published

    Exploring the solid-form landscape of pharmaceutical hydrates: transformation pathways of the sodium naproxen anhydrate-hydrate system

    Raijada, D. K., Bond, A., Larsen, F. H., Cornett, Claus, Qu, H. & Rantanen, Jukka, 2013, In: Pharmaceutical Research. 30, 1, p. 280-289 10 p.

    Research output: Contribution to journalJournal articlepeer-review

  22. Published

    Pollution Pathways of Pharmaceutical Residues in the Aquatic Environment on the Island of Mallorca, Spain

    Rodríguez-Navas, C., Björklund, E., Bak, S. A., Hansen, M., Krogh, K. A., Maya, F., Forteza, R. & Cerdà, V., 2013, In: Archives of Environmental Contamination and Toxicology. 61, 1, p. 56-66

    Research output: Contribution to journalJournal articlepeer-review

  23. Liposomal temocene (m-THPPo) photodynamic treatment induces cell death by mitochondria-independent apoptosis

    Soriano, J., Garcia-Diaz, M., Mora, M., Sagristá, M. L., Nonell, S., Villanueva, A., Stockert, J. C. & Cañete, M., 28 May 2013, In: BBA General Subjects. 1830, 10, p. 4611-4620 12 p.

    Research output: Contribution to journalJournal articlepeer-review

  24. Published

    Pattern-oriented Agent-based Monte Carlo simulation of Cellular Redox Environment

    Tang, J., Holcombe, M. & Boonen, H. C. M., 28 Aug 2013. 1 p.

    Research output: Contribution to conferencePosterResearch

  25. Published

    Prolonged naproxen joint residence time after intra-articular injection of lipophilic solutions comprising a naproxen glycolamide ester prodrug in the rat

    Thing, M., Lu, Y., Agårdh, L., Larsen, C. S., Østergaard, Jesper, He, W., Wu, W., Larsen, F. & Larsen, Susan Weng, 15 Jul 2013, In: International Journal of Pharmaceutics. 451, 1-2, p. 34-40 7 p.

    Research output: Contribution to journalJournal articlepeer-review

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